Diseases

Disease and phenotype reference pages — a comprehensive view: clinical features, associated genes and variants, GWAS signals, drug targets, clinical trials, and many more.

18616 diseases in the atlas

Amyotrophic lateral sclerosis

Summary Amyotrophic lateral sclerosis (MONDO:0004976) is a disease caused by FUS (GenCC Definitive), with 75 cohort genes (169 GWAS associations across 40 studies) and 927 clinical trials. The …

Asthma

Summary Asthma (MONDO:0004979) is a disease (an umbrella term covering 8 Mondo subtypes) with 75 cohort genes (3,219 GWAS associations across 280 studies) and 3,826 clinical trials. The dominant …

Atrial fibrillation

Summary Atrial fibrillation (MONDO:0004981) is a disease with 75 cohort genes (3,124 GWAS associations across 86 studies) and 3,017 clinical trials. The dominant Reactome pathway is Cardiac conduction …

B-cell chronic lymphocytic leukemia

Summary B-cell chronic lymphocytic leukemia (MONDO:0004948) is a cancer with 75 cohort genes (225 GWAS associations across 22 studies; 22 CIViC-evidence somatic drivers; 2 ClinVar predisposition …

Basal cell carcinoma

Summary Basal cell carcinoma (MONDO:0020804) is a cancer with 75 cohort genes (708 GWAS associations across 25 studies; 15 CIViC-evidence somatic drivers; 3 ClinVar predisposition records) and 231 …

Breast cancer

Summary Breast cancer (MONDO:0007254) is a cancer (an umbrella term covering 6 Mondo subtypes) caused by variants in BARD1 and TP53, with 79 cohort genes (626 GWAS associations across 77 studies; 70 …

Cancer

Summary Cancer (MONDO:0004992) is a cancer (an umbrella term covering 33 Mondo subtypes) with 75 cohort genes (389 GWAS associations across 69 studies; 64 CIViC-evidence somatic drivers; 5 ClinVar …

Cardiomyopathy

Summary Cardiomyopathy (MONDO:0004994) is a disease (an umbrella term covering 12 Mondo subtypes) with 75 cohort genes (56 GWAS associations across 44 studies) and 324 clinical trials. The dominant …

Cataract

Summary Cataract (MONDO:0005129) is a disease (an umbrella term covering 29 Mondo subtypes) caused by variants in CYP51A1, FOXE3, VIM, and 1 other genes, with 75 cohort genes (296 GWAS associations …

Chronic kidney disease

Summary Chronic kidney disease (MONDO:0005300) is a disease (an umbrella term covering 6 Mondo subtypes) with 75 cohort genes (421 GWAS associations across 120 studies) and 2,033 clinical trials. The …

Chronic obstructive pulmonary disease

Summary Chronic obstructive pulmonary disease (MONDO:0005002) is a disease (an umbrella term covering 5 Mondo subtypes) with 75 cohort genes (1,266 GWAS associations across 119 studies) and 3,782 …

Connective tissue disorder

Summary Connective tissue disorder (MONDO:0003900) is a disease (an umbrella term covering 16 Mondo subtypes) with 75 cohort genes (37 GWAS associations across 28 studies) and 83 clinical trials. The …

Cutaneous melanoma

Summary Cutaneous melanoma (MONDO:0005012) is a cancer (an umbrella term covering 10 Mondo subtypes) with 75 cohort genes (395 GWAS associations across 25 studies; 32 CIViC-evidence somatic drivers; 1 …

Dilated cardiomyopathy

Summary Dilated cardiomyopathy (MONDO:0005021) is a disease caused by variants in FLNC, PPP1R13L, RBM20, and 5 other genes, with 75 cohort genes (66 GWAS associations across 12 studies) and 158 …

Endometrial carcinoma

Summary Endometrial carcinoma (MONDO:0002447) is a cancer (an umbrella term covering 7 Mondo subtypes) with 75 cohort genes (117 GWAS associations across 13 studies; 35 CIViC-evidence somatic drivers; …

Epilepsy

Summary Epilepsy (MONDO:0005027) is a disease (an umbrella term covering 13 Mondo subtypes) caused by variants in GABRG2, BSN, and KCNA1, with 75 cohort genes (92 GWAS associations across 70 studies) …

Exocrine pancreatic carcinoma

Summary Exocrine pancreatic carcinoma (MONDO:0005192) is a cancer (an umbrella term covering 8 Mondo subtypes) with 75 cohort genes (303 GWAS associations across 53 studies; 27 CIViC-evidence somatic …

Glaucoma

Summary Glaucoma (MONDO:0005041) is a disease (an umbrella term covering 11 Mondo subtypes) with 75 cohort genes (860 GWAS associations across 74 studies) and 1,034 clinical trials. The dominant …

Hearing loss disorder

Summary Hearing loss disorder (MONDO:0005365) is a disease (an umbrella term covering 11 Mondo subtypes) caused by variants in GJB2 and PNPT1, with 75 cohort genes (299 GWAS associations across 70 …

Hypertensive disorder

Summary Hypertensive disorder (MONDO:0005044) is a disease (an umbrella term covering 12 Mondo subtypes) with 75 cohort genes (2,084 GWAS associations across 176 studies) and 4,735 clinical trials. …

Hypertrophic cardiomyopathy

Summary Hypertrophic cardiomyopathy (MONDO:0005045) is a disease caused by variants in ACTC1, FHOD3, MYBPC3, and 7 other genes, with 75 cohort genes (454 GWAS associations across 23 studies) and 227 …

Lung adenocarcinoma

Summary Lung adenocarcinoma (MONDO:0005061) is a disease (an umbrella term covering 11 Mondo subtypes) with 75 cohort genes (393 GWAS associations across 29 studies) and 214 clinical trials. The …

Major depressive disorder

Summary Major depressive disorder (MONDO:0002009) is a disease with 75 cohort genes (4,177 GWAS associations across 377 studies) and 2,270 clinical trials. The dominant Reactome pathway is Negative …

Retinitis pigmentosa

Summary Retinitis pigmentosa (MONDO:0019200) is a disease (an umbrella term covering 102 Mondo subtypes) caused by variants in BEST1, EYS, RAX2, and 7 other genes, with 111 cohort genes (31 GWAS …

Sugi Atlas has 18616 diseases in total. The full set is indexable by AI agents and search engines via the sitemap; most users will find a specific disease fastest via the search.