Abducens nerve disorder

Summary

Abducens nerve disorder (MONDO:0020594) is a disease. A subtype of cranial nerve neuropathy — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• ClinVar variants: 1

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	abducens nerve disorder
Mondo ID	MONDO:0020594
NCIT	C27593
SNOMED CT	398925009
UMLS	C0271355
MedGen	78767
Anatomy (UBERON)	UBERON:0001646
Is cancer (heuristic)	no

Also known as: abducens nerve disease · abducens nerve disease or disorder · abducens nerve disorder · disease of abducens nerve · disease or disorder of abducens nerve · disorder of abducens nerve · VIth nerve disorder

Data availability: 1 ClinVar variant.

Disease family

This is a subtype of cranial nerve neuropathy. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › nervous system disorder › cranial nerve neuropathy › abducens nerve disorder

Related subtypes (16): vestibulocochlear nerve disorder, ocular motility disease, hypoglossal nerve disorder, facial nerve disorder, optic nerve disorder, cranial nerve neoplasm, accessory nerve disorder, glossopharyngeal nerve disorder, olfactory nerve disorder, cranial nerve palsy, trigeminal nerve disorder, third cranial nerve disorder, pseudobulbar palsy, trochlear nerve disorder, jaw-winking syndrome, cranial neuralgia

Subtypes (2): abducens nerve neoplasm, abducens nerve palsy

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

ClinVar germline variants

1 retrieved; paginated sample, class counts are floors:

1 uncertain significance

ClinVar	Variant (HGVS)	Gene	Classification	Review
268024	46;XY;t(2;19)(q12;p13.2)dn		Uncertain significance	criteria provided, single submitter

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.