Acquired angioedema
diseaseOn this page
Also known as AAEacquired angioneurotic edemaacquired angioneurotic oedemaacquired bradykinine-induced angioedemaacquired C1 inhibitor deficiencyacquired non histamine-induced angioedemaangioedema, acquired
Summary
Acquired angioedema (MONDO:0019624) is a disease (an umbrella term covering 5 Mondo subtypes). A subtype of angioedema — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Prevalence: Unknown (Worldwide) [Orphanet-validated]
- Umbrella term: 5 Mondo subtypes
Clinical features
Epidemiology
Prevalence records
2 prevalence record(s), Orphanet:
| Type | Class | Value | Geography | Validation |
|---|---|---|---|---|
| Cases/families | 200 | Worldwide | Validated | |
| Point prevalence | 1-9 / 1 000 000 | 0.11 | Denmark | Validated |
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | acquired angioedema |
| Mondo ID | MONDO:0019624 |
| MeSH | C538173 |
| Orphanet | 91385 |
| DOID | DOID:0080941 |
| ICD-11 | 1078767412 |
| UMLS | C2931758 |
| MedGen | 419486 |
| GARD | 0008605 |
| Is cancer (heuristic) | no |
Also known as: AAE · acquired angioedema · acquired angioneurotic edema · acquired angioneurotic oedema · acquired bradykinine-induced angioedema · acquired C1 inhibitor deficiency · acquired non histamine-induced angioedema · angioedema, acquired
Disease family
This is a subtype of angioedema. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by body system or component › integumentary system disorder › skin disorder › dermatitis › urticaria › angioedema › acquired angioedema
Related subtypes (2): non-histaminic angioedema, hereditary angioedema
Subtypes (5): acquired angioedema type 2, acquired angioedema type 1, renin-angiotensin-aldosterone system-blocker-induced angioedema, acquired angioedema with C1Inh deficiency, vibratory angioedema
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 0.
Related Atlas pages
No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.