Acquired ichthyosis
diseaseOn this page
Also known as acquired ichthyosis (disease)fish scale disease, acquiredichthyosis acquisitaichthyosis, acquired
Summary
Acquired ichthyosis (MONDO:0018683) is a disease. A subtype of ichthyosis — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Prevalence: Unknown (Worldwide)
- Phenotypes (HPO): 15
Clinical features
Signs & symptoms
Clinical features (HPO)
15 HPO clinical features (Orphanet curated; top 15 by frequency):
| HPO ID | Term | Frequency |
|---|---|---|
| HP:0000958 | Dry skin | Very frequent (80-99%) |
| HP:0000989 | Pruritus | Very frequent (80-99%) |
| HP:0008064 | Ichthyosis | Very frequent (80-99%) |
| HP:0000962 | Hyperkeratosis | Frequent (30-79%) |
| HP:0000982 | Palmoplantar keratoderma | Frequent (30-79%) |
| HP:0001581 | Recurrent skin infections | Frequent (30-79%) |
| HP:0010783 | Erythema | Frequent (30-79%) |
| HP:0100326 | Immunologic hypersensitivity | Frequent (30-79%) |
| HP:0200034 | Papule | Frequent (30-79%) |
| HP:0000083 | Renal insufficiency | Occasional (5-29%) |
| HP:0002664 | Neoplasm | Occasional (5-29%) |
| HP:0002665 | Lymphoma | Occasional (5-29%) |
| HP:0002960 | Autoimmunity | Occasional (5-29%) |
| HP:0006775 | Multiple myeloma | Occasional (5-29%) |
| HP:0100242 | Sarcoma | Occasional (5-29%) |
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | acquired ichthyosis |
| Mondo ID | MONDO:0018683 |
| MeSH | C538175 |
| Orphanet | 454 |
| ICD-10-CM | L85.0 |
| ICD-11 | 1504032289 |
| NCIT | C112831 |
| SNOMED CT | 8691004 |
| UMLS | C0263386 |
| MedGen | 78092 |
| GARD | 0000476 |
| Is cancer (heuristic) | no |
Also known as: acquired ichthyosis · acquired ichthyosis (disease) · fish scale disease, acquired · ichthyosis acquisita · ichthyosis, acquired
Disease family
This is a subtype of ichthyosis. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by body system or component › integumentary system disorder › skin disorder › epidermal disease › ichthyosis › acquired ichthyosis
Related subtypes (2): inherited ichthyosis, ichthyosis, follicular
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 0.
Related Atlas pages
No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.