Acute fatty liver of pregnancy

Summary

Acute fatty liver of pregnancy (MONDO:0016573) is a disease. A subtype of acute disease — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	acute fatty liver of pregnancy
Mondo ID	MONDO:0016573
MeSH	C537957
Orphanet	243367
ICD-11	1226221530
SNOMED CT	716379000
UMLS	C1455728
MedGen	264102
GARD	0009578
MedDRA	10000746
Is cancer (heuristic)	no

Also known as: acute fatty liver, gestational · AFLP

Disease family

This is a subtype of acute disease. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › acute disease › acute fatty liver of pregnancy

Related subtypes (118): encephalopathy, acute, infection-induced, seminal vesicle acute gonorrhea, acute diarrhea, acute hydrops keratoconus, acute pericementitis, purulent acute otitis media, acute otitis externa, acute eustachian salpingitis, acute cervicitis, acute gonococcal epididymo-orchitis, acute salpingitis, acute respiratory failure, acute conjunctivitis, acute laryngopharyngitis, acute orbital inflammation, acute dacryocystitis, acute sphenoidal sinusitis, acute proliferative glomerulonephritis, acute cystitis, acute tympanitis, acute closed-angle glaucoma, acute gonococcal prostatitis, acute poststreptococcal glomerulonephritis, acute diffuse glomerulonephritis, acute retrobulbar neuritis, acute frontal sinusitis, acute cholangitis, acute thyroiditis, acute maxillary sinusitis, acute kidney injury, acute transudative otitis media, acute myocarditis, subacute glomerulonephritis, acute pyelonephritis, acute urate nephropathy, acute stress disorder, acute inflammation of lacrimal passage, acute endometritis, acute cor pulmonale, acute intestinal ischemia, subacute delirium, acute laryngitis, acute myocardial infarction, acute ethmoiditis, acute dacryoadenitis, acute female pelvic peritonitis, acute quadriplegic myopathy, severe acute respiratory syndrome, acute hypotension, acute coronary syndrome, acute chest syndrome, acute pancreatitis, acute retinal necrosis syndrome, subacute bacterial endocarditis, necrotizing encephalomyelopathy, subacute, of Leigh, adult, acute intermittent porphyria, leukemia, acute myelocytic, with polyposis coli and colon cancer, surfactant metabolism dysfunction, pulmonary, 1, myoglobinuria, acute recurrent, autosomal recessive, acute leukemia, acute insulin response, alcohol sensitivity, acute, leukemia, acute lymphocytic, susceptibility to, 1, leukemia, acute lymphocytic, susceptibility to, 2, acute infantile liver failure-cerebellar ataxia-peripheral sensory motor neuropathy syndrome, acute transverse myelitis, subacute cutaneous lupus erythematosus, acute lung injury, subacute inflammatory demyelinating polyneuropathy, Marburg acute multiple sclerosis, acute pure sensory neuropathy, autoimmune autonomic ganglionopathy, acute sensory ataxic neuropathy, acute neonatal citrullinemia type I, acute endophthalmitis, acute zonal occult outer retinopathy, acute annular outer retinopathy, poliomyelitis, acute generalized exanthematous pustulosis, acute opioid poisoning, acute encephalopathy with biphasic seizures and late reduced diffusion, acute tricyclic antidepressant poisoning, acute poisoning by drugs with membrane-stabilizing effect, recurrent acute pancreatitis, bilateral acute depigmentation of the iris, idiopathic acute eosinophilic pneumonia, acute ackee fruit intoxication, acute interstitial pneumonia, acute liver failure, acute adrenal insufficiency, encephalitis, acute inflammatory demyelinating polyradiculoneuropathy, acute motor and sensory axonal neuropathy, acute motor axonal neuropathy, acute graft versus host disease, acute pharyngitis, sudden hearing loss disorder, acute bronchiolitis, acute tonsillitis, acute rheumatic heart disease, acute cholinergic dysautonomia, acute mountain sickness, acute lymphoblastic leukemia congenital sporadic aniridia, acute lichenoid pityriasis, leukoencephalopathy, acute reversible, with increased urinary alpha-ketoglutarate, acute radiation syndrome, acute bilirubin encephalopathy, acute mast cell leukemia, subacute bursitis, acute papillary necrosis, acute posterior multifocal placoid pigment epitheliopathy, acute idiopathic urticaria, acute macular neuroretinopathy, acute flaccid myelitis, acute hepatitis B virus infection, acute hepatitis C virus infection, acute fibrinous and organizing pneumonia, acute transplant rejection

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.