Adenocarcinoma of gallbladder and extrahepatic biliary tract

Summary

Adenocarcinoma of gallbladder and extrahepatic biliary tract (MONDO:0018536) is a disease. A subtype of extrahepatic bile duct adenocarcinoma — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Prevalence: 1-9 / 100 000 (Europe) [Orphanet-validated]

Clinical features

Epidemiology

Prevalence records

1 prevalence record(s), Orphanet:

Type	Class	Value	Geography	Validation
Annual incidence	1-9 / 100 000	2.62	Europe	Validated

Identifiers

Disease identifiers

Field	Value
Canonical name	adenocarcinoma of gallbladder and extrahepatic biliary tract
Mondo ID	MONDO:0018536
Orphanet	424991
SNOMED CT	765741003
UMLS	C4707555
MedGen	1633887
GARD	0021791
Is cancer (heuristic)	no

Also known as: adenocarcinoma of gallbladder and EBT · adenocarcinoma of the gallbladder and EBT · adenocarcinoma of the gallbladder and extrahepatic biliary tract

Data availability: 2 cell lines.

Disease family

An umbrella term covering 2 Mondo subtypes.

Classification path: human disease › disease by body system or component › digestive system disorder › digestive system cancer › liver cancer › biliary tract cancer › bile duct cancer › bile duct carcinoma › extrahepatic bile duct carcinoma › extrahepatic bile duct adenocarcinoma › adenocarcinoma of gallbladder and extrahepatic biliary tract

Related subtypes (6): extrahepatic bile duct signet ring cell carcinoma, ampulla of vater adenocarcinoma, extrahepatic bile duct mucinous adenocarcinoma, extrahepatic bile duct small cell adenocarcinoma, papillary extrahepatic bile duct adenocarcinoma, extrahepatic bile duct clear cell adenocarcinoma

Subtypes (2): cholangiocarcinoma, combined hepatocellular carcinoma and cholangiocarcinoma

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.