Adult choroid plexus neoplasm
disease diseaseOn this page
Also known as adult choroid plexus tumoradult choroid plexus tumourchoroid plexus neoplasmchoroid plexus neoplasm of adultsneoplasm of adult choroid plexusneoplasm of the adult choroid plexustumor of adult choroid plexustumor of the adult choroid plexustumour of adult choroid plexustumour of the adult choroid plexus
Summary
Adult choroid plexus neoplasm (MONDO:0002683) is a cancer and 9 clinical trials. Top therapeutic interventions include bevacizumab, edotreotide gallium ga-68, and gadobenate dimeglumine. A subtype of choroid plexus neoplasm — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Classification: Cancer
- Clinical trials: 9
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | adult choroid plexus neoplasm |
| Mondo ID | MONDO:0002683 |
| DOID | DOID:3542 |
| NCIT | C8568 |
| UMLS | C0796430 |
| MedGen | 163268 |
| GARD | 0023213 |
| Is cancer (heuristic) | yes |
Also known as: adult choroid plexus neoplasm · adult choroid plexus tumor · adult choroid plexus tumour · choroid plexus neoplasm · choroid plexus neoplasm of adults · neoplasm of adult choroid plexus · neoplasm of the adult choroid plexus · tumor of adult choroid plexus · tumor of the adult choroid plexus · tumour of adult choroid plexus · tumour of the adult choroid plexus
Disease family
This is a subtype of choroid plexus neoplasm. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by body system or component › nervous system disorder › central nervous system disorder › brain disorder › brain neoplasm › choroid plexus neoplasm › adult choroid plexus neoplasm
Related subtypes (4): choroid plexus cancer, atypical choroid plexus papilloma, childhood choroid plexus neoplasm, benign choroid plexus neoplasm
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 9.
Phase distribution (across all retrieved trials)
| Phase | Trials |
|---|---|
| PHASE1 | 4 |
| Not specified | 4 |
| PHASE2 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT00492089 | PHASE2 | COMPLETED | Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck Cancer |
| NCT04541082 | PHASE1 | RECRUITING | Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms |
| NCT00110032 | PHASE1 | TERMINATED | Positron Emission Tomography Using Fluorine F 18 EF5 to Find Oxygen in Tumor Cells of Patients Who Are Undergoing Surgery or Biopsy for Newly Diagnosed Brain Tumors |
| NCT01119599 | PHASE1 | COMPLETED | RO4929097, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Malignant Glioma |
| NCT01975116 | PHASE1 | COMPLETED | p28 in Treating Younger Patients With Recurrent or Progressive Central Nervous System Tumors |
| NCT01234805 | Not specified | TERMINATED | Yoga Therapy in Treating Patients With Malignant Brain Tumors |
| NCT02162732 | Not specified | COMPLETED | Molecular-Guided Therapy for Childhood Cancer |
| NCT02194452 | Not specified | WITHDRAWN | Efficacy of 68Ga-DOTATOC Positron Emission Tomography (PET) CT in Children and Young Adults With Brain Tumors |
| NCT02967380 | Not specified | TERMINATED | Gadobutrol Versus Gadopentetate Dimeglumine or Gadobenate Dimeglumine Before DCE-MRI in Diagnosing Patients With Multiple Sclerosis, Grade II-IV Glioma, or Brain Metastases |
Drugs tested across these trials (top 30)
| Molecule | Max phase | Trials referencing |
|---|---|---|
| BEVACIZUMAB | 4 | 1 |
| EDOTREOTIDE GALLIUM GA-68 | 4 | 1 |
| GADOBENATE DIMEGLUMINE | 4 | 1 |
| GADOBUTROL | 4 | 1 |
| GADOPENTETATE DIMEGLUMINE | 4 | 1 |
| ONC-206 | 1 | 1 |