adult kidney Wilms tumor

Summary

adult kidney Wilms tumor (MONDO:0024675) is a cancer and 1 clinical trial. Top therapeutic interventions include dactinomycin and doxorubicin hydrochloride. A subtype of kidney Wilms tumor — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer
• Clinical trials: 1

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	adult kidney Wilms tumor
Mondo ID	MONDO:0024675
NCIT	C6180
UMLS	C1332219
MedGen	231045
GARD	0025456
Is cancer (heuristic)	yes

Also known as: adenosarcoma of adult kidney · adenosarcoma of the adult kidney · adult kidney adenosarcoma · adult kidney Wilms tumor · adult nephroblastoma · adult renal adenosarcoma · adult renal Wilms tumor · adult renal Wilms tumour · adult renal Wilms’ tumor · adult renal Wilms’ tumour · kidney Wilms tumor of adults · kidney Wilms tumour of adults

Disease family

This is a subtype of kidney Wilms tumor. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › cancer › malignant urinary system neoplasm › kidney cancer › kidney Wilms tumor › adult kidney Wilms tumor

Related subtypes (7): nonanaplastic kidney Wilms tumor, metachronous kidney Wilms’ tumor, mixed cell type kidney Wilms’ tumor, blastema predominant kidney Wilms tumor, epithelial predominant Wilms’ tumor, stromal predominant kidney Wilms tumor, childhood kidney Wilms tumor

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 1.

Phase distribution (across all retrieved trials)

Phase	Trials
PHASE3	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT00945009	PHASE3	ACTIVE_NOT_RECRUITING	Combination Chemotherapy and Surgery in Treating Young Patients With Wilms Tumor

Drugs tested across these trials (top 30)

Molecule	Max phase	Trials referencing
DACTINOMYCIN	4	1
DOXORUBICIN HYDROCHLORIDE	4	1
CHEMBL4748391	0	1