African histoplasmosis

Summary

African histoplasmosis (MONDO:0001262) is a disease. A subtype of Histoplasma capsulatum infectious disease — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	African histoplasmosis
Mondo ID	MONDO:0001262
DOID	DOID:11315
ICD-10-CM	B39.5
ICD-11	997943937
SNOMED CT	78511005
UMLS	C0220977
MedGen	526120
GARD	0022911
Is cancer (heuristic)	no

Also known as: African histoplasmosis · Histoplasma capsulatum var. duboisii caused disease or disorder · Histoplasma capsulatum var. duboisii disease or disorder · Histoplasma capsulatum var. duboisii infectious disease

Disease family

This is a subtype of Histoplasma capsulatum infectious disease. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › disease of primarily extrinsic mechanism › infectious disease › fungal infectious disease › systemic mycosis › primary systemic mycosis › histoplasmosis › Histoplasma capsulatum infectious disease › African histoplasmosis

Related subtypes (2): histoplasmosis retinitis, histoplasmosis meningitis

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.