Age-related hearing impairment 1

Summary

Age-related hearing impairment 1 (MONDO:0012910) is a disease and 2 clinical trials. A subtype of inherited auditory system disease — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 2

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	age-related hearing impairment 1
Mondo ID	MONDO:0012910
MeSH	C567305
OMIM	612448
UMLS	C2676230
MedGen	382794
Is cancer (heuristic)	no

Also known as: age-related hearing impairment 1 · ARHI1

Disease family

Classification path: disease › human disease › disease by body system or component › auditory system disorder › inherited auditory system disease › age-related hearing impairment 1

Related subtypes (11): otosclerosis, Meniere disease, motion sickness, Johanson-Blizzard syndrome, age-related hearing impairment 2, nonsyndromic genetic hearing loss, X-linked deafness, auditory neuropathy, tympanic paraganglioma, benign paroxysmal positional vertigo, vertigo, benign recurrent, 1

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 2.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	2

Top trials by phase / activity

NCT	Phase	Status	Title
NCT02045511	Not specified	COMPLETED	The Baltimore HEARS Pilot Study
NCT03442296	Not specified	COMPLETED	Baltimore HEARS: Hearing Health Equity Through Accessible Research & Solutions