Alexithymia
diseaseOn this page
Summary
Alexithymia (MONDO:0000661) is a disease and 22 clinical trials. Top therapeutic interventions include lufenuron. A subtype of agnosia — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Clinical trials: 22
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | alexithymia |
| Mondo ID | MONDO:0000661 |
| DOID | DOID:0060131 |
| UMLS | C0002020 |
| MedGen | 194 |
| GARD | 0027537 |
| Is cancer (heuristic) | no |
Disease family
This is a subtype of agnosia. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by body system or component › nervous system disorder › perceptual disorders › agnosia › alexithymia
Related subtypes (19): akinetopsia, amusia, anosognosia, auditory agnosia, autotopagnosia, cortical deafness, finger agnosia, integrative agnosia, mirror agnosia, pain agnosia, phonagnosia, semantic agnosia, simultanagnosia, social emotional agnosia, astereognosia, tactile agnosia, time agnosia, visual agnosia, prosopagnosia
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 22.
Phase distribution (across all retrieved trials)
| Phase | Trials |
|---|---|
| Not specified | 21 |
| PHASE2 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT05832281 | PHASE2 | TERMINATED | Role of CBD in Improving Alexithymia |
| NCT06341829 | Not specified | ENROLLING_BY_INVITATION | Visuospatial and Affective Abilities in Parkinson Disease |
| NCT06891053 | Not specified | ENROLLING_BY_INVITATION | Studio TIARA: Alessitimia ed Emicrania Cronica |
| NCT06923436 | Not specified | NOT_YET_RECRUITING | Survey of Psychological Well-being of Health Care Workers in the Hospital Setting |
| NCT07399366 | Not specified | ENROLLING_BY_INVITATION | Film-Based Medical Education and Social Justice Course: Effects on Alexithymia and Empathy in Medical Students |
| NCT07436754 | Not specified | RECRUITING | Clinical Trial Comparing the Efficacy of Two Teletherapy Programs at Improving Psychological Health in People With Brain Injury |
| NCT00830752 | Not specified | UNKNOWN | Neurobiological, Neuropsychological,Linguistic and Gestural Processes and Phenomena in Individuals With Alexithymia |
| NCT01498614 | Not specified | TERMINATED | Psychological Impact in Diabetes: Intervention With Affect School and Basal Body Awareness |
| NCT01714986 | Not specified | WITHDRAWN | Psychological Variables and Hyperglycemia in Diabetes Mellitus |
| NCT02044237 | Not specified | COMPLETED | Online Treatment of Trichotillomania |
| NCT02432300 | Not specified | COMPLETED | The Emotion Builder: An Intervention for Emotional Deficits After Brain Injury |
| NCT03312673 | Not specified | COMPLETED | Asthma, Smoking, Emotional Deficits |
| NCT03414463 | Not specified | COMPLETED | Training to Reconnect With Emotional Awareness Therapy |
| NCT04206930 | Not specified | UNKNOWN | Impact of Art Therapy on Alexithymia in People With Alcohol Use Disorder |
| NCT05076201 | Not specified | UNKNOWN | Process of Regulation in Addictions: Vulnerability Emotional Factors to Craving |
| NCT05342142 | Not specified | UNKNOWN | Effects of 12-week Exercises on Alexithymia, Depression and Quality of Life in Geriatric Individuals |
| NCT05344820 | Not specified | UNKNOWN | The Effect of the Art-based Mandala Intervention on the Quality of Life of Cancer Patients Receiving Chemotherapy |
| NCT05460806 | Not specified | COMPLETED | The Effect of Aerobic Exercise in Alexithymic Individuals With Chronic Pain |
| NCT05623046 | Not specified | COMPLETED | Building Emotional Self-Awareness Teletherapy (BEST) |
| NCT05662137 | Not specified | COMPLETED | The Effect of Recognition and Expression of Emotions Program Applied to Schizophrenia Patients |
| NCT06701097 | Not specified | COMPLETED | Emotion Regulation Training, Nursing Student, and Alexithymia |
| NCT06841302 | Not specified | COMPLETED | Alexithymia Levels in Fibromyalgia |
Drugs tested across these trials (top 30)
| Molecule | Max phase | Trials referencing |
|---|---|---|
| LUFENURON | 2 | 1 |
Related Atlas pages
No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.