Alveolar periostitis
diseaseOn this page
Also known as alveolitis of jawdry socketextrinsic allergic alveolitis of jaw skeletonjaw skeleton extrinsic allergic alveolitis
Summary
Alveolar periostitis (MONDO:0001752) is a disease and 14 clinical trials. Top therapeutic interventions include chlorhexidine, honey, and iodoform. A subtype of periostitis — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Clinical trials: 14
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | alveolar periostitis |
| Mondo ID | MONDO:0001752 |
| MeSH | D004368 |
| DOID | DOID:13585 |
| ICD-10-CM | M27.3 |
| SNOMED CT | 61804006 |
| UMLS | C0013240 |
| MedGen | 3923 |
| Is cancer (heuristic) | no |
Also known as: alveolitis of jaw · dry socket · extrinsic allergic alveolitis of jaw skeleton · jaw skeleton extrinsic allergic alveolitis
Disease family
This is a subtype of periostitis. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by body system or component › connective tissue disorder › periostitis › alveolar periostitis
Related subtypes (1): orbital periostitis
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 14.
Phase distribution (across all retrieved trials)
| Phase | Trials |
|---|---|
| Not specified | 6 |
| PHASE4 | 3 |
| PHASE2 | 2 |
| PHASE3 | 1 |
| PHASE1 | 1 |
| EARLY_PHASE1 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT06452134 | PHASE4 | NOT_YET_RECRUITING | Evaluation the Effect of Coenzyme Q10 on Tissue Healing Process in Patients Undergoing Wisdom Tooth Extraction |
| NCT03741894 | PHASE4 | UNKNOWN | Examination of the Prevention and Treatment Modalities of Alveolitis in Relation With Impacted Teeth Surgery |
| NCT05984173 | PHASE4 | COMPLETED | Role of Vitamin E in Reducing Dry Socket |
| NCT00118820 | PHASE3 | COMPLETED | Antibiotic Efficacy in Third Molar Surgery |
| NCT02678104 | PHASE2 | UNKNOWN | The Influence of Intra-alveolar Application of Honey on Healing Following Extraction |
| NCT03992144 | PHASE2 | COMPLETED | Prevention of Dry Socket by Means of Single Preoperative Antibiotics Compared to Conventional Therapy |
| NCT06456060 | PHASE1 | RECRUITING | Efficacy of Pure Honey Dressing in Contrast to Alvogyl in the Resolution of Dry Socket |
| NCT07549672 | EARLY_PHASE1 | ACTIVE_NOT_RECRUITING | Ozone Oil-based Gel and CHX Gel After Lower Third Molar Removal |
| NCT07044219 | Not specified | NOT_YET_RECRUITING | The Effect of Chlorhexidine + Hyaluronic Acid on Postoperative Wound Healing After Lower Third Molar Removal |
| NCT01292343 | Not specified | COMPLETED | Triclosan Toothpaste and Third Molar Surgery |
| NCT05536115 | Not specified | COMPLETED | Impact of Treatment With ALVEOGYL in Patients With Post-extraction Dry Socket |
| NCT05615272 | Not specified | UNKNOWN | Treatment of Alveolar Osteitis: Traditional or Regenerative? |
| NCT05875506 | Not specified | COMPLETED | Efficacy of Ozone Gel, Doxycycline Saturated Chitosan Dressing Versus Alveogyl |
| NCT06761001 | Not specified | COMPLETED | Investigation of the Effect of I-PRF Application on Pain in Alveolitis |
Drugs tested across these trials (top 30)
| Molecule | Max phase | Trials referencing |
|---|---|---|
| CHLORHEXIDINE | 4 | 1 |
| HONEY | 3 | 1 |
| IODOFORM | 3 | 1 |
Related Atlas pages
- Drugs: Chlorhexidine, Honey, Iodoform