Anal canal neuroendocrine neoplasm

Summary

Anal canal neuroendocrine neoplasm (MONDO:0003504) is a cancer. A subtype of neuroendocrine carcinoma — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	anal canal neuroendocrine neoplasm
Mondo ID	MONDO:0003504
DOID	DOID:5545
NCIT	C5603
SNOMED CT	717917007
UMLS	C1332273
MedGen	231063
GARD	0023533
Anatomy (UBERON)	UBERON:0000159
Is cancer (heuristic)	yes

Also known as: anal canal NET · anal canal neuroendocrine neoplasm · anal canal neuroendocrine tumor · anal canal neuroendocrine tumor, well differentiated, low or intermediate grade · anal canal neuroendocrine tumour · anal neuroendocrine neoplasm · anal neuroendocrine tumour · anus neuroendocrine neoplasm · anus neuroendocrine tumor · anus neuroendocrine tumour · neuroendocrine neoplasm of anal canal · neuroendocrine neoplasm of anus · neuroendocrine neoplasm of the anus · neuroendocrine tumour of anus

Disease family

This is a subtype of neuroendocrine carcinoma. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › cancer › carcinoma › neuroendocrine carcinoma › anal canal neuroendocrine neoplasm

Related subtypes (11): small cell carcinoma, large cell neuroendocrine carcinoma, pancreatic endocrine carcinoma, combined lung carcinoma, malignant adrenal gland pheochromocytoma, liver neuroendocrine carcinoma, medullary thyroid gland carcinoma, goblet cell carcinoma, cutaneous neuroendocrine carcinoma, thymic neuroendocrine carcinoma, vulvar neuroendocrine carcinoma

Subtypes (1): neuroendocrine tumor of the anal canal

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.