Anterior horn disorder

Summary

Anterior horn disorder (MONDO:0003182) is a disease. A subtype of spinal cord disorder — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	anterior horn disorder
Mondo ID	MONDO:0003182
DOID	DOID:4873
SNOMED CT	85672005
UMLS	C0154681
MedGen	102314
Anatomy (UBERON)	UBERON:0002257
Is cancer (heuristic)	no

Also known as: disease of ventral horn of spinal cord · disease or disorder of ventral horn of spinal cord · disorder of ventral horn of spinal cord · ventral horn of spinal cord disease · ventral horn of spinal cord disease or disorder

Disease family

This is a subtype of spinal cord disorder. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › nervous system disorder › central nervous system disorder › spinal cord disorder › anterior horn disorder

Related subtypes (9): vascular myelopathy, myelitis, tethered spinal cord syndrome, spina bifida, syringomyelia, radiation myelitis, spinal cord neoplasm, spinal cord injury, segmental spinal dysgenesis

Subtypes (3): spinal muscular atrophy, amyotrophic lateral sclerosis, poliomyelitis

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.