Aortitis

Summary

Aortitis (MONDO:0006656) is a disease and 5 clinical trials. A subtype of aortic disorder — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 5

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	aortitis
Mondo ID	MONDO:0006656
EFO	EFO:1000816
MeSH	D001025
DOID	DOID:519
NCIT	C97085
SNOMED CT	70933002
UMLS	C0003509
MedGen	8154
GARD	0024455
MedDRA	10002921
Is cancer (heuristic)	no

Also known as: aorta inflammation · inflammation of aorta

Disease family

This is a subtype of aortic disorder. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › cardiovascular disorder › vascular disorder › arterial disorder › aortic disorder › aortitis

Related subtypes (16): aortic atherosclerosis, aorta atresia, renal artery disease, superior mesenteric artery syndrome, aortic valve disorder, aortic malignant tumor, aortic aneurysm, tricuspid valve stenosis, tricuspid valve prolapse, aorta coarctation, subaortic stenosis, membranous, aneurysm of sinus of Valsalva, neoplasm of aortic body, Leriche syndrome, X-linked severe syndromic thoracic aortic aneurysm and dissection, fibromuscular dysplasia of the renal arteries

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 5.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	5

Top trials by phase / activity

NCT	Phase	Status	Title
NCT02967068	Not specified	RECRUITING	VCRC Tissue Repository
NCT06271018	Not specified	RECRUITING	TocILizumab in aorTitis in GCA (TILT)
NCT06866535	Not specified	RECRUITING	VIP - Vascular Infection Project
NCT01795456	Not specified	COMPLETED	Carotid Artery Neovascularization in Takayasu’s and Giant Cell Arteritis
NCT03022331	Not specified	COMPLETED	VCRC Longitudinal Protocol for Aortitis