Aseptic meningitis

Summary

Aseptic meningitis (MONDO:0006662) is a disease and 3 clinical trials. Top therapeutic interventions include acyclovir. A subtype of meningitis — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 3

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	aseptic meningitis
Mondo ID	MONDO:0006662
EFO	EFO:1000823
MeSH	D008582
DOID	DOID:12157
ICD-10-CM	G03.0
ICD-11	453360366
NCIT	C118299
SNOMED CT	301770000
UMLS	C0025290
MedGen	7534
MedDRA	10003458
Is cancer (heuristic)	no

Also known as: acute aseptic meningitis · aseptic meningitis

Disease family

This is a subtype of meningitis. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › nervous system disorder › central nervous system disorder › encephalomyelitis › meningitis › aseptic meningitis

Related subtypes (3): chronic meningitis, infectious meningitis, non-infectious meningitis

Subtypes (1): viral meningitis

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

Drugs indicated or in trials for this disease

No drug has an approved disease-direct ChEMBL indication for this disease.

1 drug in clinical trials for this disease (phase 2–3, investigational): efficacy not established — a trial record, not an indication.

Drug	Highest phase
Cytarabine	Phase 2

Clinical trials & evidence

Clinical trials

Clinical trials: 3.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	3

Top trials by phase / activity

NCT	Phase	Status	Title
NCT03418441	Not specified	RECRUITING	Central Nervous System Infections in Denmark
NCT02328469	Not specified	UNKNOWN	Aseptic Meningoencephalitis in Slovenia
NCT05586607	Not specified	COMPLETED	Causes and Management of Aseptic Meningitis : A Retrospective Cohort Study in Strasbourg University Hospital

Drugs tested across these trials (top 30)

Molecule	Max phase	Trials referencing
ACYCLOVIR	4	1