Autoimmune autonomic ganglionopathy

Summary

Autoimmune autonomic ganglionopathy (MONDO:0016499) is a disease and 1 clinical trial. A subtype of Guillain-Barre syndrome — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 1

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	autoimmune autonomic ganglionopathy
Mondo ID	MONDO:0016499
Orphanet	231457
SNOMED CT	430042004
UMLS	C2315246
MedGen	746161
GARD	0020617
Is cancer (heuristic)	no

Also known as: AAG · acute panautonomic GBS · acute panautonomic Guillain-Barre syndrome · acute panautonomic Guillain-Barré syndrome · acute panautonomic neuropathy · acute pandysautonomia · autoimmune autonomic neuropathy · idiopathic subacute autonomic neuropathy

Disease family

This is a subtype of Guillain-Barre syndrome. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › nervous system disorder › autoimmune disorder of the nervous system › autoimmune disorder of peripheral nervous system › Guillain-Barre syndrome › autoimmune autonomic ganglionopathy

Related subtypes (10): Guillain-Barre syndrome, familial, pharyngeal-cervical-brachial variant of Guillain-Barre syndrome, paraparetic variant of Guillain-Barre syndrome, acute pure sensory neuropathy, acute sensory ataxic neuropathy, facial diplegia with paresthesias, acute inflammatory demyelinating polyradiculoneuropathy, acute motor and sensory axonal neuropathy, acute motor axonal neuropathy, polyneuropathy, inflammatory demyelinating, chronic

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 1.

Phase distribution (across all retrieved trials)

Phase	Trials
PHASE2/PHASE3	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT01522235	PHASE2/PHASE3	COMPLETED	Evaluating the Effectiveness of Intravenous Immunoglobulin Therapy in Autoimmune Autonomic Ganglionopathy