Autoimmune enteropathy

Summary

Autoimmune enteropathy (MONDO:0019787) is a disease and 2 clinical trials. A subtype of autoimmune disorder of gastrointestinal tract — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 2

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	autoimmune enteropathy
Mondo ID	MONDO:0019787
MeSH	C538273
Orphanet	94075
NCIT	C94694
SNOMED CT	235728001
UMLS	C0341305
MedGen	83322
GARD	0008689
Is cancer (heuristic)	no

Also known as: immune-mediated protracted diarrhea of infancy · immune-mediated protracted diarrhoea of infancy · severe immune-mediated enteropathy

Disease family

This is a subtype of autoimmune disorder of gastrointestinal tract. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › digestive system disorder › autoimmune disorder of gastrointestinal tract › autoimmune enteropathy

Related subtypes (6): celiac disease, type 1 diabetes mellitus, autoimmune pancreatitis, autoimmune hepatitis, IgG4-related sclerosing cholangitis, autoimmune gastritis

Subtypes (4): immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome, autoimmune enteropathy and endocrinopathy - susceptibility to chronic infections syndrome, autoimmune enteropathy type 3, primary autoimmune enteropathy

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 2.

Phase distribution (across all retrieved trials)

Phase	Trials
PHASE4	1
Not specified	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT03866538	PHASE4	TERMINATED	Budesonide in Patients With Immune Mediated Enteropathies
NCT04280510	Not specified	RECRUITING	Pathogenic Study of Adult Immune Enteropathies