Balo concentric sclerosis
diseaseOn this page
Also known as Balo DiseaseBalo's concentric sclerosisBalo's diseaseBaló concentric sclerosisconcentric demyelinationdiffuse cerebral sclerosis of Schilderencephalitis periaxialis concentricaMarburg variantTumefactive multiple sclerosis
Summary
Balo concentric sclerosis (MONDO:0016430) is a disease and 1 clinical trial. A subtype of demyelinating disease — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Prevalence: Unknown (Worldwide)
- Clinical trials: 1
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | Balo concentric sclerosis |
| Mondo ID | MONDO:0016430 |
| Orphanet | 228165 |
| DOID | DOID:0060215 |
| SNOMED CT | 230380005 |
| UMLS | C0004712 |
| MedGen | 498 |
| GARD | 0005885 |
| MedDRA | 10010252 |
| NORD | 835 |
| Is cancer (heuristic) | no |
Also known as: Balo concentric sclerosis · Balo Disease · Balo disease · Balo’s concentric sclerosis · Balo’s disease · Baló concentric sclerosis · concentric demyelination · diffuse cerebral sclerosis of Schilder · encephalitis periaxialis concentrica · Marburg variant · Tumefactive multiple sclerosis
Disease family
This is a subtype of demyelinating disease. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by body system or component › nervous system disorder › central nervous system disorder › neurodegenerative disease › demyelinating disease › Balo concentric sclerosis
Related subtypes (7): demyelinating polyneuropathy, central pontine myelinolysis, polyradiculoneuropathy, Schilder disease, acute disseminated encephalomyelitis, demyelinating disease of central nervous system, boylan dew greco syndrome
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 1.
Phase distribution (across all retrieved trials)
| Phase | Trials |
|---|---|
| PHASE3 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT00004645 | PHASE3 | UNKNOWN | Phase III Randomized, Double-Blind, Sham-Controlled Study of Plasma Exchange for Acute Severe Attacks of Inflammatory Demyelinating Disease Refractory to Intravenous Methylprednisolone |
Related Atlas pages
No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.