Breast phyllodes tumor

Summary

Breast phyllodes tumor (MONDO:0021047) is a cancer and 6 clinical trials. A subtype of phyllodes tumor — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer
• Clinical trials: 6

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	breast phyllodes tumor
Mondo ID	MONDO:0021047
NCIT	C7575
SNOMED CT	712989008
UMLS	C0238031
MedGen	65943
GARD	0025279
Anatomy (UBERON)	UBERON:0000310
Is cancer (heuristic)	yes

Also known as: breast cystosarcoma phyllodes · breast phyllodes neoplasm · breast phyllodes tumor · cystosarcoma phyllodes of breast · cystosarcoma phyllodes of the breast · cystosarcoma phylloides - breast · cystosarcoma phylloides of the breast · phyllodes breast neoplasm · phyllodes breast tumor · phyllodes breast tumour · phyllodes neoplasm of breast · phyllodes neoplasm of the breast · phyllodes tumor of breast · phyllodes tumor of the breast · phyllodes tumour of breast · phyllodes tumour of the breast

Data availability: 3 cell lines.

Disease family

An umbrella term covering 2 Mondo subtypes.

Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › mixed neoplasm › fibroepithelial neoplasm › phyllodes tumor › breast phyllodes tumor

Related subtypes (3): prostate phyllodes tumor, benign phyllodes tumor, malignant phyllodes tumor

Subtypes (2): malignant breast phyllodes tumor, benign breast phyllodes tumor

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 6.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	5
PHASE1	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT03635632	PHASE1	ACTIVE_NOT_RECRUITING	C7R-GD2.CART Cells for Patients With Relapsed or Refractory Neuroblastoma and Other GD2 Positive Cancers (GAIL-N)
NCT06286267	Not specified	RECRUITING	AI-Assisted System for Accurate Diagnosis and Prognosis of Breast Phyllodes Tumors
NCT03030677	Not specified	COMPLETED	Establishing Technique for PECS2 Catheter Insertion
NCT03868475	Not specified	WITHDRAWN	Comparing Vacuum-Assisted Percutaneous Excision to Open Surgical Excision for Borderline or High-Risk Breast Lesions
NCT04571307	Not specified	UNKNOWN	Cryotherapy in Breast B3 Lesions
NCT06780059	Not specified	COMPLETED	Effects of Radiotherapy in Borderline and Malignant Phyllodes Tumors After R0 Resection