Cancer-related condition

Summary

Cancer-related condition (MONDO:0045054) is a cancer and 50 clinical trials. Top therapeutic interventions include dexamethasone, dronabinol, and glutamine. A subtype of cancer or benign tumor — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer
• Clinical trials: 50

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	cancer-related condition
Mondo ID	MONDO:0045054
NCIT	C8278
UMLS	C0280950
MedGen	128925
Is cancer (heuristic)	yes

Also known as: cancer related problem/condition · cancer-related condition · cancer-related problem or condition · oncologic complications · problem/condition, cancer related · problem/condition, cancer-related

Disease family

This is a subtype of cancer or benign tumor. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › cancer-related condition

Related subtypes (4): hyperplasia, polyp, precancerous condition, neoplastic disease or syndrome

Subtypes (2): gastric linitis plastica, paraneoplastic syndrome

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 50.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	39
PHASE2	5
PHASE1/PHASE2	2
EARLY_PHASE1	2
PHASE4	1
PHASE3	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT04155008	PHASE4	TERMINATED	Nutrition and Pharmacological Algorithm for Oncology Patients Study
NCT00006994	PHASE3	TERMINATED	S9908: Glutamine in Treating Mucositis Caused by Radiation Therapy in Patients With Newly Diagnosed Cancer of the Mouth or Throat
NCT05333250	PHASE1/PHASE2	RECRUITING	Modafinil to Improve Fatiguability
NCT01540019	PHASE1/PHASE2	UNKNOWN	Paullinia Cupana for Anorexia in Oncologic Patients
NCT02970500	PHASE2	TERMINATED	Effect of Methylphenidate on Cancer-related Cognitive Impairment
NCT03282214	PHASE2	COMPLETED	A Self-Management Energy Conservation Program for Cancer-Related Fatigue
NCT03911921	PHASE2	COMPLETED	RSYR for Fatigue Reduction in Cancer Survivors
NCT04950608	PHASE2	COMPLETED	Pilot Study of Psilocybin-Assisted Therapy for Demoralization in Patients Receiving Hospice Care
NCT05229029	PHASE2	UNKNOWN	RSYR for Fatigue Reduction in Cancer Fatigue Caused by Chemotherapy
NCT02823314	EARLY_PHASE1	UNKNOWN	Effectiveness of Medical Taping Concept in Cancer Patients
NCT05344625	EARLY_PHASE1	WITHDRAWN	Ketamine-Assisted PsychoTherapy ViAbility in Treating Cancer-related Emotional Distress
NCT02872532	Not specified	RECRUITING	Testicular Tissue Cryopreservation in Children
NCT04533165	Not specified	ACTIVE_NOT_RECRUITING	Virtual Exercise Program to Reduce Cancer Related Fatigue
NCT04940780	Not specified	RECRUITING	Integrative Oncology for Patient Symptoms
NCT05226078	Not specified	ACTIVE_NOT_RECRUITING	The Association Between CBT-I Dose, Sleep Duration, and Fatigue in Breast Cancer Patients
NCT05546736	Not specified	NOT_YET_RECRUITING	iCanWork: A Randomized Controlled Trial
NCT05710809	Not specified	RECRUITING	The SaVe Project-Sarcopenia and Vertigo in Aging Patients With Colorectal Cancer
NCT05891431	Not specified	ACTIVE_NOT_RECRUITING	Engagement and Acceptability of the Untire mHealth App
NCT06717178	Not specified	RECRUITING	Cancer and Aging Research Group (CARG) Chemotherapy Toxicity Risk Scores in Older Adults With Cancer in China
NCT06754722	Not specified	RECRUITING	Decentralized Clinical Trial of Effectiveness of EnergyPoints App in Cancer Survivors
NCT06809101	Not specified	RECRUITING	Home Monitoring of Complete Blood Count Performed by Patients - a Pilot Study on the Implementation Process in South Baltic Countries.
NCT06839794	Not specified	RECRUITING	Effect of Cognitively Challenging Physical Activity on Executive Functions in Pediatric Cancer Patients
NCT01196442	Not specified	COMPLETED	Electrical Stimulation Pain Therapy in Treating Chronic Pain and Numbness Caused By Chemotherapy in Patients With Cancer
NCT01541111	Not specified	COMPLETED	Magnesium Associated With Morphine for Cancer Pain Relief
NCT01967836	Not specified	COMPLETED	Glad Press ’n Seal® as a Temporary Moisture Barrier to Central Lines in Ambulatory Patients
NCT02468141	Not specified	COMPLETED	Effect of Sipjeondaebo-tang for Cancer Related Anorexia in Cancer Patients
NCT02827552	Not specified	TERMINATED	Description of Individual Radiosensitivity With Molecular Biomarkers in a Pediatric Oncology Population
NCT03187275	Not specified	COMPLETED	Efficacy of Massage for the Treatment of Cancer-Related Fatigue (CRF) in Prostate Cancer Survivors
NCT03194399	Not specified	COMPLETED	Development of Personalized Health Care Service in Patients With Breast Cancer
NCT03198754	Not specified	COMPLETED	Programmed Environmental Illumination (PEI) of Hospital Rooms to Prevent/Reduce Cancer-Related Fatigue
NCT03217201	Not specified	COMPLETED	Systematic Light Exposure for Fatigue in Breast Cancer Patients
NCT03345264	Not specified	COMPLETED	The Find Your PATHS (Pragmatic Assessment of a Tool to Help Survivors) to Sexual Health and Parenthood Study
NCT03533413	Not specified	COMPLETED	Combined Fluoroscopy and CT Guided Radiofrequency Ablation of Thoracic Dorsal Root Ganglia in Severe Thoracic Pain
NCT03576274	Not specified	COMPLETED	Combined Technology Enhanced Home Exercise Program and Other Non-pharmacological Intervention for Cancer Survivors
NCT03645005	Not specified	COMPLETED	A Research Study for Latina Women After Breast Cancer Treatment
NCT03650322	Not specified	COMPLETED	Effects of Yoga, Strength Training and Aerobic Exercise on Cognition in Adult Cancer Survivors
NCT03882580	Not specified	UNKNOWN	Reporting, Evaluating, Preventing and Treating the Cardiotoxicity Induced by Anticancer Drugs During a Specific Cardio-oncology Consult and Follow up in Routine Care
NCT04064151	Not specified	COMPLETED	A Research Study for Latina Women Undergoing Breast Cancer Treatment
NCT04168814	Not specified	COMPLETED	Nutritional Status in Locally Advanced or Metastatic Solid Cancer Patients in Spain: the NutriOncoSearch (NOS) Study
NCT04230941	Not specified	COMPLETED	Memory and Attention Adaptation Training-Geriatrics (MAAT-G)

Drugs tested across these trials (top 30)

Molecule	Max phase	Trials referencing
DEXAMETHASONE	4	1
DRONABINOL	4	1
GLUTAMINE	4	1
MIRTAZAPINE	4	1
MODAFINIL	4	1
PSILOCYBIN	3	1
MEBUFOTENIN	2	1