Carotid artery occlusion
diseaseOn this page
Also known as carotid artery segment occlusion precerebral arteryocclusion precerebral artery of carotid artery segment
Summary
Carotid artery occlusion (MONDO:0004450) is a disease and 4 clinical trials. Top therapeutic interventions include clopidogrel. A subtype of occlusion precerebral artery — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Clinical trials: 4
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | carotid artery occlusion |
| Mondo ID | MONDO:0004450 |
| DOID | DOID:807 |
| SNOMED CT | 266254007 |
| UMLS | C0265101 |
| MedGen | 539079 |
| Anatomy (UBERON) | UBERON:0005396 |
| Is cancer (heuristic) | no |
Also known as: carotid artery segment occlusion precerebral artery · occlusion precerebral artery of carotid artery segment
Disease family
This is a subtype of occlusion precerebral artery. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by body system or component › nervous system disorder › central nervous system disorder › brain disorder › cerebrovascular disorder › occlusion precerebral artery › carotid artery occlusion
Related subtypes (2): vertebral artery occlusion, basilar artery occlusion
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 4.
Phase distribution (across all retrieved trials)
| Phase | Trials |
|---|---|
| Not specified | 3 |
| PHASE3 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT01758614 | PHASE3 | COMPLETED | The Carotid and Middle Cerebral Artery Occlusion Surgery Study |
| NCT06702644 | Not specified | NOT_YET_RECRUITING | Safety and Efficacy of Remote Ischemic Conditioning in Patients with Chronic Internal Carotid Artery Occlusion Receiving Hybird Surgery: a Pilot, Randomized Controlled Trial |
| NCT07396025 | Not specified | ENROLLING_BY_INVITATION | Effectiveness of Surgical and Diagnostic Methods in Cerebral Vascular Occlusive Disease |
| NCT04291430 | Not specified | UNKNOWN | Multi-dimensional Evaluation System for Recanalization of Symptomatic Non-acute Carotid Artery Occlusion |
Drugs tested across these trials (top 30)
| Molecule | Max phase | Trials referencing |
|---|---|---|
| CLOPIDOGREL | 4 | 1 |
Related Atlas pages
- Drugs: Clopidogrel