Cerebral palsy spastic hemiplegic

Summary

Cerebral palsy spastic hemiplegic (MONDO:0022699) is a disease and 25 clinical trials. A subtype of spastic hemiplegia — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 25

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	cerebral palsy spastic hemiplegic
Mondo ID	MONDO:0022699
UMLS	C0837177
MedGen	208850
Is cancer (heuristic)	no

Also known as: spastic hemiplegia cerebral palsy · spastic hemiplegic cerebral palsy

Disease family

This is a subtype of spastic hemiplegia. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › nervous system disorder › central nervous system disorder › palsy › cerebral palsy › spastic cerebral palsy › spastic hemiplegia › cerebral palsy spastic hemiplegic

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 25.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	25

Top trials by phase / activity

NCT	Phase	Status	Title
NCT03402854	Not specified	RECRUITING	tDCS and Bimanual Therapy for Children With Hemiplegic Cerebral Palsy
NCT06473298	Not specified	RECRUITING	Role of Light Tracking Intervention in Children With Spastic Hemiplegia
NCT06753812	Not specified	ENROLLING_BY_INVITATION	Investigation of the Effect of Constraint Induced Movement Therapy Applied to the Lower Extremity on Lower Extremity Functions in Individuals With Unilateral Cerebral Palsy
NCT07007858	Not specified	ENROLLING_BY_INVITATION	Effects of High-Velocity Passive Stretch on Spasticity, Function, and Muscle Structure in Spastic CP Children
NCT07065916	Not specified	ENROLLING_BY_INVITATION	Arm More + Camp: An Implementation Study
NCT07247812	Not specified	RECRUITING	tSCS in Children and Young People With HCP
NCT07347795	Not specified	ACTIVE_NOT_RECRUITING	Effect of Blood Flow Restriction Training Exercises on Hand Grip Strength in Hemiparetic Cerebral Palsied Children
NCT07493096	Not specified	RECRUITING	Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disorders
NCT02010736	Not specified	COMPLETED	Loading Gait in Spatic Cerebral Palsy
NCT02458612	Not specified	COMPLETED	Effects of Mirror Therapy Combined With Progressive Strength Training in Unilateral Spastic Cerebral Palsy
NCT02460406	Not specified	COMPLETED	Progressive Functional Strength Training in Unilateral Spastic Cerebral Palsy
NCT03612128	Not specified	COMPLETED	The Effect of Mirror Therapy on Cerebral Re-organization, Functional Motor Skills, and Quality of Life in Hemiplegic Cerebral Palsy
NCT03858335	Not specified	COMPLETED	Therapeutic Effects of Constraint-Induced Movement Therapy on Young Children With Cerebral Palsy
NCT04064788	Not specified	COMPLETED	Modified Constraint-Induced Movement Therapy in Children With Hemiparetic Cerebral Palsy
NCT04154566	Not specified	COMPLETED	Influence of Aerobic Exercise on Inhibitory Control of Excutive Function in Spastic Hemiplegic C.P
NCT04171232	Not specified	COMPLETED	Effect of Augmented Reality Intervention on the Range of Motion, Muscle Strength, Function of Upper Extremity and Balance in Children With Spastic Hemiplegic Cerebral Palsy: A Randomized Clinical Trial
NCT04884386	Not specified	COMPLETED	Effects of WALKBOT-G Robot-assisted Gait Training on Anticipatory Posture Adjustment Function and Balance With Cerebral Palsy
NCT05094921	Not specified	COMPLETED	Halliwick Concept on Motor Functions in Spastic CP
NCT05261048	Not specified	UNKNOWN	Pelvic Proprioceptive Neuromuscular Facilitation on Trunk Control and Balance
NCT05593406	Not specified	COMPLETED	Mechanical Vibration on Children With Cerebral Palsy
NCT06352762	Not specified	COMPLETED	The Effects of Upper Extremity Robotic Rehabilitation in Children With Spastic Hemiparetic Cerebral Palsy
NCT06560281	Not specified	COMPLETED	Improving Hand Movements in Kids With One-Sided Arm Stiffness Cerebral Palsy Through Motion Minder Therapy (MoMT)
NCT07114731	Not specified	COMPLETED	Comparison of Synchronous and Asynchronous Action Observation Therapy in Children With Cerebral Palsy
NCT07136129	Not specified	COMPLETED	Functional Exercise Performance in Children With Cerebral Palsy: Is the One-Minute Sit-to-Stand Test an Alternative to the Six-Minute Walk Test
NCT07233031	Not specified	COMPLETED	Effectiveness of Universal Exercise Unit Exercise on Upper Limb Strength Using Biodex Isokinetic

Drugs tested across these trials (top 30)

Molecule	Max phase	Trials referencing
CHEMBL443232	0	2