Cerebral primitive neuroectodermal tumor

Summary

Cerebral primitive neuroectodermal tumor (MONDO:0004209) is a cancer and 2 clinical trials. A subtype of cerebral hemisphere cancer — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer
• Clinical trials: 2

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	cerebral primitive neuroectodermal tumor
Mondo ID	MONDO:0004209
DOID	DOID:7398
NCIT	C4970
UMLS	C0751675
MedGen	155905
GARD	0027669
Is cancer (heuristic)	yes

Also known as: cerebral hemisphere PNET · cerebral hemisphere primitive neuroectodermal neoplasm · cerebral hemisphere primitive neuroectodermal tumor · cerebral hemisphere primitive neuroectodermal tumour · cerebral PNET · cerebral primitive neuroectodermal neoplasm · cerebral primitive neuroectodermal tumor · PNET of cerebral hemispheres · PNET of cerebrum · PNET of the cerebral hemispheres · PNET of the cerebrum · primitive neuroectodermal neoplasm of cerebral hemispheres · primitive neuroectodermal neoplasm of cerebrum · primitive neuroectodermal neoplasm of the cerebral hemispheres · primitive neuroectodermal neoplasm of the cerebrum · primitive neuroectodermal tumor of cerebral hemispheres · primitive neuroectodermal tumor of cerebrum · primitive neuroectodermal tumor of the cerebral hemispheres · primitive neuroectodermal tumor of the cerebrum · primitive neuroectodermal tumour of cerebral hemispheres (+3 more)

Disease family

Classification path: disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › cancer › nervous system cancer › central nervous system cancer › brain cancer › supratentorial cancer › cerebral hemisphere cancer › cerebral primitive neuroectodermal tumor

Related subtypes (9): corpus callosum oligodendroglioma, parietal lobe cancer, temporal lobe cancer, cerebral neuroblastoma, cerebral lymphoma, cerebral meningioma, childhood cerebral astrocytoma, pediatric cerebral ependymoblastoma, frontal lobe ependymal tumor

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 2.

Phase distribution (across all retrieved trials)

Phase	Trials
PHASE1	1
Not specified	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT02457845	PHASE1	COMPLETED	HSV G207 Alone or With a Single Radiation Dose in Children With Progressive or Recurrent Supratentorial Brain Tumors
NCT02238899	Not specified	COMPLETED	Multicenter Register for Children and Young Adults With Intracranial Localized Medulloblastoma, CNS-PNET or Ependymoma