Chemotherapy-induced oral mucositis
disease diseaseOn this page
Summary
Chemotherapy-induced oral mucositis (MONDO:0005588) is a disease and 5 clinical trials. Top therapeutic interventions include chamomile and quercetin. A subtype of stomatitis — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Clinical trials: 5
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | chemotherapy-induced oral mucositis |
| Mondo ID | MONDO:0005588 |
| UMLS | C2887631 |
| MedGen | 853868 |
| Is cancer (heuristic) | no |
Disease family
This is a subtype of stomatitis. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by developmental or physiological process › inflammatory disease › mucositis › stomatitis › chemotherapy-induced oral mucositis
Related subtypes (6): gingivitis, aphthous stomatitis, ulcerative stomatitis, canker sore, herpes simplex virus gingivostomatitis, denture stomatitis
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 5.
Phase distribution (across all retrieved trials)
| Phase | Trials |
|---|---|
| PHASE2 | 2 |
| Not specified | 2 |
| PHASE1/PHASE2 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT01732393 | PHASE1/PHASE2 | COMPLETED | Effect of Quercetin in Prevention and Treatment of Oral Mucositis |
| NCT03348241 | PHASE2 | COMPLETED | Using Gum Arabic for Cancer Patients to Protect From Oral Mucositis Caused by Chemotherapy: ِِِAn Experimental Study |
| NCT06214273 | PHASE2 | UNKNOWN | Low Level Diode Laser Versus Topical Chamomile in Management of Chemotherapy Induced Oral Mucositis |
| NCT07327476 | Not specified | NOT_YET_RECRUITING | Effect of Oral Ice Chips to Prevent Chemotherapy-Induced Oral Mucositis in Patient With Solid Tumor Treated With 5 Fluorouracil and Methotrexate |
| NCT07491536 | Not specified | RECRUITING | Ozone Therapy With Biomimetic Oral Care for Cancer-Related Oral Mucositis |
Drugs tested across these trials (top 30)
| Molecule | Max phase | Trials referencing |
|---|---|---|
| CHAMOMILE | 3 | 1 |
| QUERCETIN | 3 | 1 |