Childhood central nervous system embryonal carcinoma

Summary

Childhood central nervous system embryonal carcinoma (MONDO:0004153) is a cancer. A subtype of childhood central nervous system germ cell tumor — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	childhood central nervous system embryonal carcinoma
Mondo ID	MONDO:0004153
DOID	DOID:7231
NCIT	C6208
UMLS	C1377605
MedGen	277988
GARD	0023853
Is cancer (heuristic)	yes

Also known as: childhood central nervous system embryonal carcinoma · childhood CNS embryonal cell carcinoma · childhood embryonal carcinoma of the central nervous system · embryonal carcinoma of childhood central nervous system · embryonal carcinoma of childhood CNS · embryonal carcinoma of paediatric central nervous system · embryonal carcinoma of pediatric central nervous system · embryonal carcinoma of pediatric CNS · embryonal carcinoma of the central nervous system of childhood · embryonal carcinoma of the childhood central nervous system · embryonal carcinoma of the childhood CNS · embryonal carcinoma of the paediatric central nervous system · embryonal carcinoma of the paediatric CNS · embryonal carcinoma of the pediatric central nervous system · embryonal carcinoma of the pediatric CNS · paediatric central nervous system embryonal carcinoma · paediatric CNS embryonal cell carcinoma · paediatric embryonal carcinoma of the central nervous system · pediatric central nervous system embryonal carcinoma · pediatric embryonal carcinoma of the central nervous system

Disease family

This is a subtype of childhood central nervous system germ cell tumor. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › nervous system disorder › central nervous system disorder › central nervous system neoplasm › central nervous system germ cell tumor › childhood central nervous system germ cell tumor › childhood central nervous system embryonal carcinoma

Related subtypes (7): central nervous system endodermal sinus tumor, childhood central nervous system mature teratoma, pediatric CNS choriocarcinoma, childhood central nervous system immature teratoma, childhood germ cell brain tumor, childhood central nervous system mixed germ cell tumor, childhood central nervous system germinoma

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.