Childhood central nervous system primitive neuroectodermal neoplasm
diseaseOn this page
Also known as Central nervous system embryonal tumor, NOScentral nervous system primitive neuroectodermal neoplasm of childhoodchildhood central nervous system PNETchildhood central nervous system primitive neuroectodermal tumorchildhood central nervous system primitive neuroectodermal tumourchildhood central primitive neuroectodermal neoplasmchildhood central primitive neuroectodermal tumorchildhood central primitive neuroectodermal tumourchildhood CNS PNETchildhood CNS primitive neuroectodermal neoplasmchildhood CNS primitive neuroectodermal tumorchildhood CNS primitive neuroectodermal tumourpaediatric central nervous system primitive neuroectodermal neoplasmpaediatric central nervous system primitive neuroectodermal tumourpaediatric central primitive neuroectodermal neoplasmpaediatric central primitive neuroectodermal tumourpaediatric CNS PNETpaediatric CNS primitive neuroectodermal neoplasmpaediatric CNS primitive neuroectodermal tumour
Summary
Childhood central nervous system primitive neuroectodermal neoplasm (MONDO:0002798) is a cancer and 1 clinical trial. A subtype of central nervous system primitive neuroectodermal neoplasm — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Classification: Cancer
- Clinical trials: 1
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | childhood central nervous system primitive neuroectodermal neoplasm |
| Mondo ID | MONDO:0002798 |
| DOID | DOID:3870 |
| NCIT | C5961 |
| UMLS | C1332957 |
| MedGen | 232347 |
| GARD | 0027621 |
| Is cancer (heuristic) | yes |
Also known as: Central nervous system embryonal tumor, NOS · central nervous system primitive neuroectodermal neoplasm of childhood · childhood central nervous system PNET · childhood central nervous system primitive neuroectodermal neoplasm · childhood central nervous system primitive neuroectodermal tumor · childhood central nervous system primitive neuroectodermal tumour · childhood central primitive neuroectodermal neoplasm · childhood central primitive neuroectodermal tumor · childhood central primitive neuroectodermal tumour · childhood CNS PNET · childhood CNS primitive neuroectodermal neoplasm · childhood CNS primitive neuroectodermal tumor · childhood CNS primitive neuroectodermal tumour · paediatric central nervous system primitive neuroectodermal neoplasm · paediatric central nervous system primitive neuroectodermal tumour · paediatric central primitive neuroectodermal neoplasm · paediatric central primitive neuroectodermal tumour · paediatric CNS PNET · paediatric CNS primitive neuroectodermal neoplasm · paediatric CNS primitive neuroectodermal tumour (+7 more)
Disease family
This is a subtype of central nervous system primitive neuroectodermal neoplasm. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › cancer › nervous system cancer › central nervous system cancer › central nervous system primitive neuroectodermal neoplasm › childhood central nervous system primitive neuroectodermal neoplasm
Related subtypes (7): adult central nervous system primitive neuroectodermal neoplasm, intracranial primitive neuroectodermal tumor, spinal cord neuroblastoma, ganglioneuroma, spinal cord primitive neuroectodermal tumor, ependymoblastoma, central nervous system tumor with bcor internal tandem duplication
Subtypes (2): pediatric infratentorial ependymoblastoma, pediatric cerebral ependymoblastoma
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 1.
Phase distribution (across all retrieved trials)
| Phase | Trials |
|---|---|
| PHASE2 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT00003460 | PHASE2 | COMPLETED | Antineoplaston Therapy in Treating Children With Primitive Neuroectodermal Tumors |
Related Atlas pages
No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.