Chlamydia trachomatis infectious disease
diseaseOn this page
Also known as Chlamydia trachomatis caused disease or disorderChlamydia trachomatis disease or disorderChlamydial infection
Summary
Chlamydia trachomatis infectious disease (MONDO:0005701) is a disease and 9 clinical trials. Top therapeutic interventions include doxycycline anhydrous. A subtype of commensal bacterial infectious disease — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Clinical trials: 9
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | chlamydia trachomatis infectious disease |
| Mondo ID | MONDO:0005701 |
| EFO | EFO:0007205 |
| DOID | DOID:11263 |
| NCIT | C34463 |
| SNOMED CT | 105629000 |
| Is cancer (heuristic) | no |
Also known as: Chlamydia trachomatis caused disease or disorder · Chlamydia trachomatis disease or disorder · Chlamydial infection
Disease family
This is a subtype of commensal bacterial infectious disease. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by etiologic mechanism › disease of primarily extrinsic mechanism › infectious disease › bacterial infectious disease › commensal bacterial infectious disease › chlamydia trachomatis infectious disease
Related subtypes (5): toxic shock syndrome, actinomycosis, gas gangrene, Lemierre syndrome, staphylococcal scalded skin syndrome
Subtypes (4): trachoma, inclusion conjunctivitis, lymphogranuloma venereum, pneumonia caused by chlamydia
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
Drugs indicated for this disease
0 approved, 3 in late-stage (phase 3) trials. Disease-direct ChEMBL indications, not inferred from the associated-gene cohort below.
| Drug | Development status |
|---|---|
| Azithromycin | Phase 3 (in late-stage trials) |
| Erythromycin | Phase 3 (in late-stage trials) |
| Silver Nitrate | Phase 3 (in late-stage trials) |
Earlier-phase candidates (phase 2, investigational — efficacy not yet established): Amoxicillin, Rifalazil.
Clinical trials & evidence
Clinical trials
Clinical trials: 9.
Phase distribution (across all retrieved trials)
| Phase | Trials |
|---|---|
| Not specified | 5 |
| PHASE3 | 2 |
| PHASE4 | 1 |
| PHASE2 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT05840159 | PHASE4 | COMPLETED | A Study of Doxycycline to Treat Chlamydial Infection |
| NCT00262106 | PHASE3 | COMPLETED | Trial to Evaluate PRO 2000/5 Gels for the Prevention of Vaginally Acquired HIV Infection |
| NCT00980148 | PHASE3 | COMPLETED | Treatment Failure of Chlamydial Infection in Males and Females in Youth Correctional Facilities |
| NCT03249935 | PHASE2 | COMPLETED | YCFM (Youth Correctional Facilities Males) |
| NCT07094373 | Not specified | RECRUITING | Validation of Chlamydia Diagnostic Codes in TriNetX US EHR Data |
| NCT01849653 | Not specified | COMPLETED | Self-Obtained Vaginal Swabs for Chlamydia and Gonorrhea Testing |
| NCT03596151 | Not specified | TERMINATED | Clinical Study of a Single-Use, Point-of-Care Molecular Diagnostic Device for the Detection of Neisseria Gonorrhoeae (NG), Trichomonas Vaginalis (TV), and Chlamydia Trachomatis (CT) Utilizing Vaginal Swabs |
| NCT03852316 | Not specified | COMPLETED | Clinical Study of a Diagnostic Device for NG, TV and CT in Women |
| NCT04098900 | Not specified | COMPLETED | Clinical Evaluation of the Click Sexual Health Test for the Detection of Neisseria Gonorrhoeae (NG), Trichomonas Vaginalis (TV), and Chlamydia Trachomatis (CT) in Women |
Drugs tested across these trials (top 30)
| Molecule | Max phase | Trials referencing |
|---|---|---|
| DOXYCYCLINE ANHYDROUS | 4 | 6 |
Related Atlas pages
- Drugs: Doxycycline