Choroid neoplasm
diseaseOn this page
Also known as choroid tumorchoroid tumourchoroidal neoplasmchoroidal tumorchoroidal tumourneoplasm of choroidneoplasm of optic choroidneoplasm of the choroidoptic choroid neoplasmoptic choroid neoplasm (disease)optic choroid tumoroptic choroid tumourtumor of choroidtumor of optic choroidtumor of the choroidtumour of choroidtumour of optic choroidtumour of the choroid
Summary
Choroid neoplasm (MONDO:0021258) is a cancer and 3 clinical trials. A subtype of optic choroid disorder — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Classification: Cancer
- Clinical trials: 3
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | choroid neoplasm |
| Mondo ID | MONDO:0021258 |
| NCIT | C2949 |
| UMLS | C0008523 |
| MedGen | 3059 |
| Anatomy (UBERON) | UBERON:0001776 |
| Is cancer (heuristic) | yes |
Also known as: choroid tumor · choroid tumour · choroidal neoplasm · choroidal tumor · choroidal tumour · neoplasm of choroid · neoplasm of optic choroid · neoplasm of the choroid · optic choroid neoplasm · optic choroid neoplasm (disease) · optic choroid tumor · optic choroid tumour · tumor of choroid · tumor of optic choroid · tumor of the choroid · tumour of choroid · tumour of optic choroid · tumour of the choroid
Disease family
This is a subtype of optic choroid disorder. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by body system or component › disorder of orbital region › eye disorder › uveal disorder › optic choroid disorder › choroid neoplasm
Related subtypes (6): choroiditis, retinal dystrophies primarily involving Bruch’s membrane, choroidal sclerosis, central areolar choroidal dystrophy, ornithine aminotransferase deficiency, choroideremia
Subtypes (2): choroid cancer, benign neoplasm of choroid
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 3.
Phase distribution (across all retrieved trials)
| Phase | Trials |
|---|---|
| PHASE3 | 1 |
| PHASE1 | 1 |
| Not specified | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT00000124 | PHASE3 | UNKNOWN | Collaborative Ocular Melanoma Study (COMS) |
| NCT02771340 | PHASE1 | COMPLETED | Study Evaluating Single and Repeated Intravitreal Doses of ICON-1 in Patients With Uveal Melanoma |
| NCT00406120 | Not specified | WITHDRAWN | Validation of a Molecular Prognostic Test for Eye Melanoma |
Related Atlas pages
No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.