Choroidal sclerosis

Summary

Choroidal sclerosis (MONDO:0004885) is a disease. A subtype of optic choroid disorder — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	choroidal sclerosis
Mondo ID	MONDO:0004885
MeSH	C535358
DOID	DOID:980
SNOMED CT	406446000
UMLS	C0344297
MedGen	137998
Anatomy (UBERON)	UBERON:0001776
Is cancer (heuristic)	no

Also known as: choroidal degenerations · neurodegenerative disease of optic choroid · optic choroid neurodegenerative disease

Disease family

This is a subtype of optic choroid disorder. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › disorder of orbital region › eye disorder › uveal disorder › optic choroid disorder › choroidal sclerosis

Related subtypes (6): choroiditis, retinal dystrophies primarily involving Bruch’s membrane, central areolar choroidal dystrophy, ornithine aminotransferase deficiency, choroideremia, choroid neoplasm

Subtypes (4): senile atrophy of choroid, angioid streaks of choroid, hereditary choroidal atrophy, diffuse secondary choroid atrophy

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.