Chromomycosis

Summary

Chromomycosis (MONDO:0015908) is a disease and 1 clinical trial. A subtype of subcutaneous mycosis — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Prevalence: Unknown (Worldwide)
• Phenotypes (HPO): 33
• Clinical trials: 1

Clinical features

Signs & symptoms

Clinical features (HPO)

33 HPO clinical features (Orphanet curated; top 33 by frequency):

HPO ID	Term	Frequency
HP:0000989	Pruritus	Very frequent (80-99%)
HP:0002814	Abnormality of the lower limb	Very frequent (80-99%)
HP:0000962	Hyperkeratosis	Frequent (30-79%)
HP:0000969	Edema	Frequent (30-79%)
HP:0001004	Lymphedema	Frequent (30-79%)
HP:0001482	Subcutaneous nodule	Frequent (30-79%)
HP:0001760	Abnormal foot morphology	Frequent (30-79%)
HP:0003550	Predominantly lower limb lymphedema	Frequent (30-79%)
HP:0012500	Verrucous papule	Frequent (30-79%)
HP:0025474	Erythematous plaque	Frequent (30-79%)
HP:0025475	Erythematous macule	Frequent (30-79%)
HP:0025527	Serpiginous cutaneous lesion	Frequent (30-79%)
HP:0025528	Annular cutaneous lesion	Frequent (30-79%)
HP:0040009	Hyperparakeratosis	Frequent (30-79%)
HP:0045059	Hyperkeratotic papule	Frequent (30-79%)
HP:0000987	Atypical scarring of skin	Occasional (5-29%)
HP:0001053	Hypopigmented skin patches	Occasional (5-29%)
HP:0002718	Recurrent bacterial infections	Occasional (5-29%)
HP:0002817	Abnormality of the upper limb	Occasional (5-29%)
HP:0011276	Vascular skin abnormality	Occasional (5-29%)
HP:0031842	Lymphangiectasis	Occasional (5-29%)
HP:0000163	Abnormal oral cavity morphology	Very rare (<1-4%)
HP:0000491	Keratitis	Very rare (<1-4%)
HP:0000656	Ectropion	Very rare (<1-4%)
HP:0001097	Keratoconjunctivitis sicca	Very rare (<1-4%)
HP:0002088	Abnormal lung morphology	Very rare (<1-4%)
HP:0002721	Immunodeficiency	Very rare (<1-4%)
HP:0002797	Osteolysis	Very rare (<1-4%)
HP:0002860	Squamous cell carcinoma	Very rare (<1-4%)
HP:0007606	Multiple cutaneous malignancies	Very rare (<1-4%)
HP:0011334	Facial shape deformation	Very rare (<1-4%)
HP:0031013	Ankylosis	Very rare (<1-4%)
HP:0500043	Eyelid retraction	Very rare (<1-4%)

Identifiers

Disease identifiers

Field	Value
Canonical name	chromomycosis
Mondo ID	MONDO:0015908
EFO	EFO:0007207
MeSH	D002862
Orphanet	182
DOID	DOID:1562
ICD-11	1438584733
SNOMED CT	187079000
UMLS	C0008582
MedGen	3434
GARD	0001319
MedDRA	10008803
Is cancer (heuristic)	no

Also known as: Chromoblastomycoses · chromoblastomycosis · Chromomycoses · Chromomycosis · chromomycosis · dermatitis Verrucosa

Disease family

Classification path: disease › human disease › disease by etiologic mechanism › disease of primarily extrinsic mechanism › infectious disease › fungal infectious disease › cutaneous mycosis › subcutaneous mycosis › chromomycosis

Related subtypes (1): conidiobolomycosis

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 1.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT06523998	Not specified	COMPLETED	A Study on Rare Dermatological Infections Conducted at Three Major Reference Hospitals in Costa Rica.