Chromosome 18 mosaic monosomy

Summary

Chromosome 18 mosaic monosomy (MONDO:0022755) is a disease. A subtype of monosomy — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	chromosome 18 mosaic monosomy
Mondo ID	MONDO:0022755
MeSH	C536581
UMLS	C2931250
MedGen	419755
GARD	0003726
Is cancer (heuristic)	no

Also known as: monosomy 18 mosaicism · Mosaic monosomy 18 · Mosaic monosomy chromosome 18

Disease family

Classification path: disease › human disease › disease by etiologic mechanism › disease of genetic or genomic mechanism › chromosomal disorder › aneuploidy › monosomy › chromosome 18 mosaic monosomy

Related subtypes (3): monosomy 22, monosomy X, monosomy chromosome 8

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.