Chronic endometritis

Summary

Chronic endometritis (MONDO:0024279) is a disease and 12 clinical trials. Top therapeutic interventions include 17. A subtype of endometritis — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 12

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	chronic endometritis
Mondo ID	MONDO:0024279
ICD-11	440849195
NCIT	C102820
SNOMED CT	63922003
UMLS	C0238104
MedGen	536766
Is cancer (heuristic)	no

Also known as: chronic endometritis · endometritis, chronic

Disease family

This is a subtype of endometritis. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › reproductive system disorder › female reproductive system disorder › uterine disorder › endometrial disorder › endometritis › chronic endometritis

Related subtypes (2): acute endometritis, endomyometritis

Subtypes (2): non specific chronic endometritis, granulomatous endometritis

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 12.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	7
PHASE1/PHASE2	2
PHASE2	2
PHASE4	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT07485842	PHASE4	NOT_YET_RECRUITING	FuKe Qianjin Capsule Plus Antibiotics for Chronic Endometritis
NCT07180563	PHASE1/PHASE2	RECRUITING	Randomized Controlled Trial of Berberine in Combination With Doxycycline in the Treatment of Chronic Endometritis
NCT04432467	PHASE1/PHASE2	COMPLETED	Fertility Restoration Using Autologous Mesenchymal Stem Cells
NCT04447625	PHASE2	COMPLETED	Intrauterine Antibiotic Infusion in Treating Chronic Endometritis and Restoring Reproductive Dynamics
NCT05205993	PHASE2	UNKNOWN	Εffectiveness of Intrauterine Antibiotic Administration for Treatment of Chronic Endometritis
NCT07488949	Not specified	RECRUITING	Doxycycline and Progestin Therapy for Chronic Endometritis(CE) in Patients With Recurrent Reproductive Failure(RRF)
NCT02646930	Not specified	COMPLETED	Chronic Endometritis and IVF
NCT02648698	Not specified	COMPLETED	RCT(Randomized Clinical Trial ) of Antibiotic Therapy in Chronic Endometritis
NCT02680275	Not specified	COMPLETED	Efficacy of Dead Sea Peloid Gel in Chronic Endometritis
NCT02744807	Not specified	COMPLETED	Role of Chronic Endometritis in Postoperative Recurrence of Severe Intrauterine Adhesions
NCT03169621	Not specified	TERMINATED	Diagnosis of Chronic Endometritis in Endometrial Fluid Using Molecular Techniques to Improve the Outcomes of Assisted Reproductive Treatments
NCT06890754	Not specified	COMPLETED	Hysteroscopy for Chronic Endometritis: Diagnostic Performance and Observer Variability

Drugs tested across these trials (top 30)

Molecule	Max phase	Trials referencing
17	0	1