Coinfection

Summary

Coinfection (MONDO:0100128) is a disease and 11 clinical trials. Top therapeutic interventions include boceprevir, peginterferon alfa-2a, and peginterferon alfa-2b. A subtype of infectious disease — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 11

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	coinfection
Mondo ID	MONDO:0100128
MeSH	D060085
UMLS	C0275524
MedGen	452372
Is cancer (heuristic)	no

Disease family

This is a subtype of infectious disease. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › disease of primarily extrinsic mechanism › infectious disease › coinfection

Related subtypes (34): infective endocarditis, hirudiniasis, fungal infectious disease, infectious peritonitis, epididymitis, viral infectious disease, bacterial infectious disease, parasitic infectious disease, abscess, Ciliophora infectious disease, hookworm infectious disease, infectious embryofetopathy, mycetoma, infectious disorder of the nervous system, ear infection, sexually transmitted disease, puerperal infection, Acanthamoeba infectious disease, infectious myositis, infective vaginitis, skin disorder caused by infection, respiratory tract infectious disorder, nail infection, infective arthritis, digestive system infectious disorder, nosocomial infection, eye infectious disorder, prosthesis-related infectious disease, vector-borne disease, urinary tract infection, hemorrhagic fever, protothecosis, pythiosis, infectious disease with sepsis

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 11.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	10
PHASE3	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT01718301	PHASE3	TERMINATED	HIV Patients With Chronic Hepatitis C Genotype 1 Infection Who Failed Previously to Peginterferon /Ribavirin
NCT02699736	Not specified	ENROLLING_BY_INVITATION	EuroSIDA - Clinical and Virological Outcome of European Patients Infected With HIV
NCT04984772	Not specified	ENROLLING_BY_INVITATION	Prospective Cohort of HIV/HBV-coinfected Patients in Europe
NCT06834178	Not specified	NOT_YET_RECRUITING	Non-interventional Study to Assess the Number of People With Untreated/Unknown HBV + HDV and HCV in South-East Austria
NCT02325102	Not specified	COMPLETED	Effects of Viral and Bacterial Co-infections in Otherwise Healthy Children Hospitalized in Pediatric Department
NCT03800381	Not specified	COMPLETED	Adequacy of the New Pediatric Isoniazid/Rifampin/Pyrazinamide (HRZ) Tablet
NCT03800394	Not specified	COMPLETED	Pharmacokinetics of Intracellular TFV-DP and FTC-TP in HIV-infected Adolescents
NCT03800407	Not specified	COMPLETED	Contributing Factors for Poor HIV Treatment Response in Children With TB/HIV Coinfection
NCT04410263	Not specified	UNKNOWN	Microbiota in COVID-19 Patients for Future Therapeutic and Preventive Approaches
NCT05318235	Not specified	COMPLETED	Virus Interactions in the Respiratory Tract; a Cohort Study With Children
NCT06779175	Not specified	COMPLETED	Analysis of Single Respiratory Viral Infections Versus Co-infections: Prevalence and ICU Needs in Hospitalized Adults

Drugs tested across these trials (top 30)

Molecule	Max phase	Trials referencing
BOCEPREVIR	4	1
PEGINTERFERON ALFA-2A	4	1
PEGINTERFERON ALFA-2B	4	1
CHEMBL4868590	0	1