Colorectal sessile serrated adenoma/polyp

Summary

Colorectal sessile serrated adenoma/polyp (MONDO:0006164) is a cancer and 3 clinical trials. A subtype of colorectal adenoma — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer
• Clinical trials: 3

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	colorectal sessile serrated adenoma/polyp
Mondo ID	MONDO:0006164
EFO	EFO:1000197
NCIT	C83176
UMLS	C2826783
MedGen	415420
Is cancer (heuristic)	yes

Also known as: colorectal mixed hyperplastic adenomatous polyp · colorectal mixed hyperplastic adenomatous polyp/serrated adenoma · colorectal sessile serrated adenoma · colorectal sessile serrated adenoma/polyp · colorectal sessile serrated polyp · colorectal SSA · colorectal SSA/P · colorectal SSP

Disease family

This is a subtype of colorectal adenoma. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › digestive system disorder › intestinal disorder › intestinal neoplasm › colorectal neoplasm › colorectal adenoma › colorectal sessile serrated adenoma/polyp

Related subtypes (3): colon adenoma, rectum adenoma, colorectal tubulovillous adenoma

Subtypes (1): colon sessile serrated adenoma/polyp

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 3.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	3

Top trials by phase / activity

NCT	Phase	Status	Title
NCT04196088	Not specified	UNKNOWN	To Compare Artificial Intelligence Software Aided Adenoma Detection in Screening Colonoscopies Versus Standard Colonoscopy Without Artificial Intelligence Software Assistance in Participants Between 45 and 75 Years of Age
NCT04723758	Not specified	COMPLETED	COLO-DETECT: Can an Artificial Intelligence Device Increase Detection of Polyps During Colonoscopy?
NCT05576506	Not specified	COMPLETED	Application of Hyperspectral Imaging Analysis Technology in the Diagnosis of Colorectal Cancer Based on Colonoscopic Biopsy