Complex sleep apnea

Summary

Complex sleep apnea (MONDO:0024358) is a disease and 3 clinical trials. A subtype of central sleep apnea syndrome — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 3

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	complex sleep apnea
Mondo ID	MONDO:0024358
DOID	DOID:0080302
SNOMED CT	230493001
UMLS	C0338495
MedGen	83271
Is cancer (heuristic)	no

Also known as: complex sleep apnea · CompSAS

Disease family

This is a subtype of central sleep apnea syndrome. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › syndromic disease › central sleep apnea syndrome › complex sleep apnea

Related subtypes (4): primary central sleep apnea syndrome, drug induced central sleep apnea, central sleep apnea due to periodic breathing, central sleep apnea caused by high altitude

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 3.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	3

Top trials by phase / activity

NCT	Phase	Status	Title
NCT01609244	Not specified	COMPLETED	Bilevel Versus Servoventilation in Complex Sleep Apnea
NCT03032029	Not specified	COMPLETED	Registry on the Treatment of Central and Complex Sleep-Disordered Breathing With Adaptive Servo-Ventilation
NCT03421704	Not specified	COMPLETED	A Prospective Multicenter Registry of Patients With Sleep Disordered Breathing Treated With DreamStation BiPAP autoSV.