Connective and soft tissue neoplasm
diseaseOn this page
Also known as connective and soft tissue tumorconnective and soft tissue tumourmusculoskeletal and soft tissue neoplasmmusculoskeletal and soft tissue tumormusculoskeletal and soft tissue tumourneoplasm of skeletal and soft tissueneoplasm of soft tissue and boneneoplasm of soft tissue and skeletonskeletal and soft tissue neoplasmskeletal and soft tissue tumorskeletal and soft tissue tumoursoft tissue and bone neoplasmsoft tissue and bone tumorsoft tissue and bone tumourtumor of skeletal and soft tissuetumor of soft tissue and bonetumor of soft tissue and skeletontumour of skeletal and soft tissuetumour of soft tissue and bone
Summary
Connective and soft tissue neoplasm (MONDO:0044334) is a cancer and 3 clinical trials. Top therapeutic interventions include rivoceranib. A subtype of neoplasm — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Classification: Cancer
- Clinical trials: 3
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | connective and soft tissue neoplasm |
| Mondo ID | MONDO:0044334 |
| NCIT | C3810 |
| UMLS | C0206765 |
| MedGen | 60224 |
| Is cancer (heuristic) | yes |
Also known as: connective and soft tissue neoplasm · connective and soft tissue tumor · connective and soft tissue tumour · musculoskeletal and soft tissue neoplasm · musculoskeletal and soft tissue tumor · musculoskeletal and soft tissue tumour · neoplasm of skeletal and soft tissue · neoplasm of soft tissue and bone · neoplasm of soft tissue and skeleton · skeletal and soft tissue neoplasm · skeletal and soft tissue tumor · skeletal and soft tissue tumour · soft tissue and bone neoplasm · soft tissue and bone tumor · soft tissue and bone tumour · tumor of skeletal and soft tissue · tumor of soft tissue and bone · tumor of soft tissue and skeleton · tumour of skeletal and soft tissue · tumour of soft tissue and bone (+1 more)
Disease family
This is a subtype of neoplasm. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › connective and soft tissue neoplasm
Related subtypes (47): pre-malignant neoplasm, endocrine gland neoplasm, giant cell tumor, hematopoietic and lymphoid system neoplasm, skin neoplasm, mesenchymal cell neoplasm, epidural spinal canal neoplasm, skeletal muscle neoplasm, trophoblastic neoplasm, cancer, germ cell tumor, benign neoplasm, upper aerodigestive tract neoplasm, histiocytoma, embryonal neoplasm, head and neck neoplasm, epithelial neoplasm, reproductive system neoplasm, non-seminomatous lesion, odontogenic cyst, phosphaturic mesenchymal tumor, thyroglossal duct cyst, hamartoma, mesenchymoma, mesothelial neoplasm, peritoneal neoplasm, virus associated tumor, nail tumor, respiratory tract neoplasm, spindle cell neoplasm, mixed neoplasm, urinary system neoplasm, cystic neoplasm, childhood neoplasm, melanocytic neoplasm, digestive system neoplasm, nervous system neoplasm, neoplasm of thorax, connective tissue neoplasm, bronchial adenomas/carcinoids childhood, diffuse idiopathic pulmonary neuroendocrine cell hyperplasia, erythroplakia, retroperitoneal neoplasm, cardiovascular neoplasm, dermoid or epidermoid cyst of the central nervous system, NTRK fusion positive cancer, RET fusion positive cancer
Subtypes (3): benign connective and soft tissue neoplasm, soft tissue neoplasm, synovial chondromatosis
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 3.
Phase distribution (across all retrieved trials)
| Phase | Trials |
|---|---|
| PHASE2 | 1 |
| PHASE1 | 1 |
| Not specified | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT03539172 | PHASE2 | UNKNOWN | Radiotherapy Concurrent With Apatinib in Advanced Soft Tissue and Bone Sarcomas of Head and Neck–RASS Study |
| NCT02602067 | PHASE1 | TERMINATED | 131Iodine-Tenatumomab Treatment in Tenascin-C Positive Cancer Patients |
| NCT02199938 | Not specified | TERMINATED | Identification and Characterization of Molecular Markers in Musculoskeletal Tumors |
Drugs tested across these trials (top 30)
| Molecule | Max phase | Trials referencing |
|---|---|---|
| RIVOCERANIB | 3 | 1 |
Related Atlas pages
- Drugs: Rivoceranib