Corneal infection

Summary

Corneal infection (MONDO:0023865) is a disease (an umbrella term covering 7 Mondo subtypes) and 5 clinical trials. A subtype of keratitis — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Umbrella term: 7 Mondo subtypes
• Clinical trials: 5

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	corneal infection
Mondo ID	MONDO:0023865
Orphanet	519278
NCIT	C83813
SNOMED CT	312428002
UMLS	C0729777
MedGen	152673
Anatomy (UBERON)	UBERON:0000964
Is cancer (heuristic)	no

Also known as: corneal infection · infection of cornea · infective keratitis · keratitis caused by infection

Disease family

This is a subtype of keratitis. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › disorder of orbital region › eye disorder › corneal disorder › keratitis › corneal infection

Related subtypes (10): macular keratitis, superficial keratitis, photokeratitis, scleroperikeratitis, filamentary keratitis, corneal ulcer, keratoconjunctivitis, deep keratitis, corneal neovascularization, autosomal dominant keratitis

Subtypes (7): corneal abscess, epidemic keratoconjunctivitis, gonococcal keratitis, Acanthamoeba keratitis, herpes simplex virus keratitis, infectious epithelial keratitis, fungal keratitis

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 5.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	4
EARLY_PHASE1	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT06967376	EARLY_PHASE1	COMPLETED	The Role of Adjuvant Corneal Crosslinking in the Management of Infective Keratitis
NCT05888987	Not specified	RECRUITING	Use of a New Method for the Microbiological Diagnosis of Severe Corneal Infection
NCT04894630	Not specified	COMPLETED	Infective Keratitis in Minia Governate
NCT04969640	Not specified	COMPLETED	Role of Anterior Segment Optical Coherence Tomography in Infectious Keratitis
NCT05387993	Not specified	COMPLETED	Microbial Keratitis in Cairo University Hospitals