Cortical blindness
diseaseOn this page
Also known as cerebral visual impairmentcortical visual impairmentcortical/cerebral visual impairmentCVI
Summary
Cortical blindness (MONDO:0001385) is a disease and 19 clinical trials. A subtype of blindness (disorder) — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Clinical trials: 19
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | cortical blindness |
| Mondo ID | MONDO:0001385 |
| MeSH | D019575 |
| DOID | DOID:11831 |
| ICD-10-CM | H47.61 |
| NCIT | C118707 |
| SNOMED CT | 68574006 |
| UMLS | C0155320 |
| MedGen | 57834 |
| GARD | 0027575 |
| Is cancer (heuristic) | no |
Also known as: cerebral visual impairment · cortical visual impairment · cortical/cerebral visual impairment · CVI
Disease family
This is a subtype of blindness (disorder). Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by body system or component › nervous system disorder › perceptual disorders › vision disorder › blindness (disorder) › cortical blindness
Related subtypes (3): night blindness, microcephaly microphthalmos blindness, amaurosis fugax
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 19.
Phase distribution (across all retrieved trials)
| Phase | Trials |
|---|---|
| Not specified | 19 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT05085210 | Not specified | RECRUITING | Improving Visual Field Deficits With Noninvasive Brain Stimulation |
| NCT06121219 | Not specified | RECRUITING | Effect of Visual Retraining After Stroke |
| NCT06636994 | Not specified | ACTIVE_NOT_RECRUITING | Anatomical and Functional Predictions of Blindsight Capabilities in Patients With Lateral Hemianopsia |
| NCT06701617 | Not specified | RECRUITING | In-person and Telehealth Visual Rehabilitation for Children With Low Vision |
| NCT07105358 | Not specified | RECRUITING | Visual Plasticity Following Brain Lesions |
| NCT07134777 | Not specified | RECRUITING | Mechanisms of Visual Restoration After Occipital Stroke |
| NCT07212010 | Not specified | ENROLLING_BY_INVITATION | Neurodevelopmental Outcomes in Cerebral Visual Impairment |
| NCT07427719 | Not specified | NOT_YET_RECRUITING | Retinopathy of Prematurity - Visual Function and Retinal Structure |
| NCT00342108 | Not specified | COMPLETED | Cortical Visual Impairment and Visual Attentiveness |
| NCT03957980 | Not specified | COMPLETED | Remote Access: Cortical Visual Impairment |
| NCT04051983 | Not specified | COMPLETED | iVision - Development of a Game-based Therapy for Children With Cerebral Visual Impairment |
| NCT05014503 | Not specified | COMPLETED | A Computerized, Adaptive Therapeutic Gaming Approach Training Visual Perceptual Skills in Children With CVI |
| NCT05048550 | Not specified | UNKNOWN | Babies in Glasses; a Feasibility Study. |
| NCT05102955 | Not specified | COMPLETED | Turkish Validity and Reliability of the Visual Function Classification System (VFCS) |
| NCT06067607 | Not specified | UNKNOWN | Examining the Effect of Eye Gaze Technology on Children With Cortical Visual Impairment |
| NCT06352086 | Not specified | WITHDRAWN | Understanding Visual Processing After Occipital Stroke |
| NCT06599996 | Not specified | COMPLETED | Artificial Intelligence and Augmentative and Alternative Communication AAC |
| NCT06827743 | Not specified | COMPLETED | Feeding Behavior Intervention in Children with Cerebral Visual Impairment |
| NCT07492966 | Not specified | COMPLETED | Exosomes Effect on Visual Function in CVI |
Related Atlas pages
No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.