Cubital tunnel syndrome
diseaseOn this page
Also known as cubital tunnel syndromessyndrome, cubital tunnelsyndromes, cubital tunneltunnel syndrome, cubitaltunnel syndromes, cubitalulnar nerve compression, cubital tunnelulnar nerve entrapment, elbow
Summary
Cubital tunnel syndrome (MONDO:0043982) is a disease and 28 clinical trials. Top therapeutic interventions include indocyanine green acid form and poliglusam. A subtype of ulnar neuropathy — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Clinical trials: 28
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | cubital tunnel syndrome |
| Mondo ID | MONDO:0043982 |
| MeSH | D020430 |
| SNOMED CT | 56177003 |
| UMLS | C0206239 |
| MedGen | 104813 |
| GARD | 0025874 |
| Is cancer (heuristic) | no |
Also known as: cubital tunnel syndrome · cubital tunnel syndromes · syndrome, cubital tunnel · syndromes, cubital tunnel · tunnel syndrome, cubital · tunnel syndromes, cubital · ulnar nerve compression, cubital tunnel · ulnar nerve entrapment, elbow
Disease family
This is a subtype of ulnar neuropathy. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by body system or component › nervous system disorder › peripheral nervous system disorder › peripheral neuropathy › mononeuropathy › ulnar neuropathy › cubital tunnel syndrome
Related subtypes (1): ulnar nerve lesion
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 28.
Phase distribution (across all retrieved trials)
| Phase | Trials |
|---|---|
| Not specified | 25 |
| PHASE4 | 1 |
| PHASE3 | 1 |
| PHASE2 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT05332405 | PHASE4 | WITHDRAWN | SPY Angiography To Assist With Ulnar Nerve Transposition at the Elbow |
| NCT02739945 | PHASE3 | COMPLETED | Sonographic Examination Cubital Tunnel Release |
| NCT01109901 | PHASE2 | COMPLETED | Comparison of Effect of Anterior Subcutaneous and Submuscular Transposition on Cubital Tunnel Syndrome |
| NCT04662320 | Not specified | ACTIVE_NOT_RECRUITING | Promoting Healing of Nerves Through Electrical Stimulation |
| NCT05395715 | Not specified | RECRUITING | Conditioning Electrical Stimulation to Improve Outcomes in Cubital Tunnel Syndrome |
| NCT06117501 | Not specified | ACTIVE_NOT_RECRUITING | Nerve Protection Evaluation: Revision Cubital Tunnel Syndrome Decompression |
| NCT07001111 | Not specified | RECRUITING | Investigation of the Effectiveness of Kinesiological Taping in Cubital Tunnel Syndrome |
| NCT07496398 | Not specified | RECRUITING | Median and Ulnar Nerve Function in Tattoo Artists |
| NCT07522060 | Not specified | NOT_YET_RECRUITING | Early Functional Response as a Predictor of Clinical Outcomes in Hand Rehabilitation: A Prospective Feasibility Study Using a Digital Monitoring System |
| NCT00184158 | Not specified | COMPLETED | Treatment for Cubital Tunnel Syndrome |
| NCT01394822 | Not specified | COMPLETED | Neuromuscular Ultrasound for Focal Neuropathies |
| NCT01693094 | Not specified | SUSPENDED | A Randomized Trial Measuring the Effect of Decision Aids on Patients’ Satisfaction, Conflict of Decision-making and Clinical Outcome |
| NCT01781494 | Not specified | WITHDRAWN | Immobilization Versus Immediate Motion After Anterior Submuscular Ulnar Nerve Transposition |
| NCT01893164 | Not specified | UNKNOWN | Comparison of Different Surgical Treatments for Different Scales of Cubital Tunnel Syndrome |
| NCT02466841 | Not specified | WITHDRAWN | Prospective Comparison of Techniques for Cubital Tunnel Release |
| NCT02566616 | Not specified | WITHDRAWN | Electrical Nerve Stimulation of the Ulnar Nerve |
| NCT02677506 | Not specified | COMPLETED | Infraclavicular or Supraclavicular Brachial Plexus Blocks for Elbow Surgery |
| NCT02801461 | Not specified | COMPLETED | The Effect of ESWT for Cubital Tunnel Syndrome |
| NCT02995382 | Not specified | WITHDRAWN | Health-Related Quality of Life in Cases of Cubital Tunnel Syndrome |
| NCT03629470 | Not specified | COMPLETED | Effectiveness of Nerve Glide Exercises on Cubital Tunnel Syndrome |
| NCT03651609 | Not specified | COMPLETED | Treatment for Ulnar Neuropathy at the Elbow |
| NCT04322448 | Not specified | COMPLETED | Mechanomyography for Predictor of Prognosis in CuTS and PND Patients |
| NCT04470245 | Not specified | UNKNOWN | Cubital Tunnel Syndrome and Diffusion MRI: A Proof of Concept Study |
| NCT04647058 | Not specified | WITHDRAWN | Randomized Trial of Supercharged End-to-Side Anterior Interosseous Nerve Transfer for Severe Cubital Tunnel Syndrome |
| NCT04658511 | Not specified | UNKNOWN | Presence of the Arcade of Struthers on Preoperative Ultrasound |
| NCT05212311 | Not specified | COMPLETED | Effect of Chitosan Phonophoresis On Cubital Tunnel Syndrome |
| NCT05931731 | Not specified | UNKNOWN | Mechanical Interference Versus Neural Mobilization on Ulnar Neuropathy Post Cubital Tunnel Syndrome |
| NCT06095011 | Not specified | SUSPENDED | Posture Correction in Cubital Tunnel Syndrome |
Drugs tested across these trials (top 30)
| Molecule | Max phase | Trials referencing |
|---|---|---|
| INDOCYANINE GREEN ACID FORM | 4 | 2 |
| POLIGLUSAM | 3 | 1 |