Cutaneous leiomyosarcoma

Summary

Cutaneous leiomyosarcoma (MONDO:0003362) is a disease. A subtype of leiomyosarcoma — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	cutaneous leiomyosarcoma
Mondo ID	MONDO:0003362
DOID	DOID:5273
ICD-11	1653448241
NCIT	C4484
SNOMED CT	254771006
UMLS	C0346067
MedGen	87534
GARD	0023476
Anatomy (UBERON)	UBERON:0000014
Is cancer (heuristic)	no

Also known as: cutaneous leiomyosarcoma · cutaneous leiomyosarcoma (disease) · leiomyosarcoma of skin · leiomyosarcoma of the skin · leiomyosarcoma of zone of skin · skin leiomyosarcoma · zone of skin leiomyosarcoma

Data availability: 1 HPO phenotype.

Disease family

This is a subtype of leiomyosarcoma. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › musculoskeletal system disorder › musculoskeletal system cancer › muscle cancer › smooth muscle cancer › leiomyosarcoma › cutaneous leiomyosarcoma

Related subtypes (30): fallopian tube leiomyosarcoma, bone leiomyosarcoma, inflammatory leiomyosarcoma, conventional leiomyosarcoma, central nervous system leiomyosarcoma, colon leiomyosarcoma, heart leiomyosarcoma, ovary leiomyosarcoma, epithelioid leiomyosarcoma, lung leiomyosarcoma, myxoid leiomyosarcoma, small intestine leiomyosarcoma, gallbladder leiomyosarcoma, esophagus leiomyosarcoma, gastric leiomyosarcoma, prostate leiomyosarcoma, vagina leiomyosarcoma, retroperitoneal leiomyosarcoma, breast leiomyosarcoma, vulvar leiomyosarcoma, kidney leiomyosarcoma, laryngeal leiomyosarcoma, mediastinum leiomyosarcoma, liver leiomyosarcoma, rectum leiomyosarcoma, pulmonary vein leiomyosarcoma, pulmonary artery leiomyosarcoma, superior vena cava leiomyosarcoma, leiomyosarcoma of the corpus uteri, leiomyosarcoma of the cervix uteri

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.