Cutaneous undifferentiated pleomorphic sarcoma

Summary

Cutaneous undifferentiated pleomorphic sarcoma (MONDO:0002141) is a cancer. A subtype of undifferentiated pleomorphic sarcoma — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	cutaneous undifferentiated pleomorphic sarcoma
Mondo ID	MONDO:0002141
DOID	DOID:1906
ICD-11	361875781
NCIT	C5576
SNOMED CT	404014008
UMLS	C1275254
MedGen	224813
GARD	0023075
Anatomy (UBERON)	UBERON:0000014
Is cancer (heuristic)	yes

Also known as: cutaneous malignant fibrous histiocytoma · cutaneous unclassified pleomorphic sarcoma · cutaneous unclassified pleomorphic sarcoma (formerly cutaneous \ · cutaneous unclassified pleomorphic sarcoma (formerly cutaneous \ · cutaneous unclassified pleomorphic sarcoma (formerly cutaneous) · cutaneous undifferentiated pleomorphic sarcoma · malignant cutaneous fibrous histiocytoma · malignant fibrous histiocytoma of skin · malignant fibrous histiocytoma of the skin · malignant skin fibrous histiocytoma · undifferentiated pleomorphic sarcoma of zone of skin · zone of skin undifferentiated pleomorphic sarcoma

Disease family

This is a subtype of undifferentiated pleomorphic sarcoma. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › histiocytoma › undifferentiated pleomorphic sarcoma › cutaneous undifferentiated pleomorphic sarcoma

Related subtypes (2): malignant giant cell tumor of soft parts, undifferentiated pleomorphic sarcoma, inflammatory variant

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.