Dermoid cyst
disease diseaseOn this page
Also known as benign cystic teratomadermoiddermoid cyst, benigndermoid tumormature cystic teratomasubcutaneous cystic teratoma
Summary
Dermoid cyst (MONDO:0002378) is a disease (an umbrella term covering 5 Mondo subtypes) and 3 clinical trials. Top therapeutic interventions include imatinib and vactosertib. A subtype of cystic teratoma — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Umbrella term: 5 Mondo subtypes
- Clinical trials: 3
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | dermoid cyst |
| Mondo ID | MONDO:0002378 |
| MeSH | D003884 |
| DOID | DOID:2658 |
| ICD-11 | 1622534741 |
| NCIT | C9011 |
| SNOMED CT | 441459009 |
| UMLS | C0011649 |
| MedGen | 41504 |
| GARD | 0023127 |
| Is cancer (heuristic) | no |
Also known as: benign cystic teratoma · dermoid · dermoid cyst · dermoid cyst, benign · dermoid tumor · mature cystic teratoma · subcutaneous cystic teratoma
Disease family
This is a subtype of cystic teratoma. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › germ cell tumor › nongerminomatous germ cell tumor › teratoma › cystic teratoma › dermoid cyst
Related subtypes (2): ovarian cystic teratoma, adult cystic teratoma
Subtypes (5): dermoid cyst of skin, spinal cord dermoid cyst, dermoid cyst of ovary, cervical dermoid cyst, facial dermoid cyst
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 3.
Phase distribution (across all retrieved trials)
| Phase | Trials |
|---|---|
| Not specified | 2 |
| PHASE2 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT06219733 | PHASE2 | WITHDRAWN | Vactosertib and Imatinib Combination in Patients with Advanced Desmoid Tumor/aggressive Fibromatosis (DT/AF) |
| NCT03823833 | Not specified | COMPLETED | Oocyte Freezing for Fertility Preservation in Benign Ovarian Tumors |
| NCT06816316 | Not specified | COMPLETED | Role of Alcohol in Prevention of Recurrence of the Accidentally Opened Angular Dermoid Cyst |
Drugs tested across these trials (top 30)
| Molecule | Max phase | Trials referencing |
|---|---|---|
| IMATINIB | 4 | 1 |
| VACTOSERTIB | 2 | 1 |
| CHEMBL5267324 | 0 | 1 |
Related Atlas pages
- Drugs: Imatinib