Descending colon cancer

Summary

Descending colon cancer (MONDO:0001462) is a cancer and 1 clinical trial. A subtype of malignant colon neoplasm — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer
• Clinical trials: 1

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	descending colon cancer
Mondo ID	MONDO:0001462
DOID	DOID:12190
ICD-10-CM	C18.6
SNOMED CT	363409003
UMLS	C0153435
MedGen	509291
Anatomy (UBERON)	UBERON:0001158
Is cancer (heuristic)	yes

Also known as: cancer of descending colon · descending colon cancer · malignant descending colon neoplasm · malignant neoplasm of descending colon · malignant tumour of descending colon

Disease family

This is a subtype of malignant colon neoplasm. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › digestive system disorder › intestinal disorder › large intestine disorder › colonic disorder › colonic neoplasm › malignant colon neoplasm › descending colon cancer

Related subtypes (8): sigmoid colon cancer, colon carcinoma, cecum cancer, colon lymphoma, ascending colon cancer, transverse colon cancer, colon sarcoma, metastasis from malignant tumor of colon

Subtypes (1): splenic flexure cancer

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 1.

Phase distribution (across all retrieved trials)

Phase	Trials
PHASE2	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT01861691	PHASE2	UNKNOWN	Randomized Controlled Trial Between Laparoscopic and Open Surgery in Transverse and Descending Colon Cancer Patients