Desmoplastic infantile astrocytoma

Summary

Desmoplastic infantile astrocytoma (MONDO:0022963) is a disease. A subtype of mixed neuronal-glial tumor — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	desmoplastic infantile astrocytoma
Mondo ID	MONDO:0022963
NCIT	C9476
UMLS	C0457179
MedGen	141595
GARD	0009617
Is cancer (heuristic)	no

Also known as: Desmoplastic astrocytoma of infancy · Desmoplastic infantile astrocytoma · DIA

Disease family

This is a subtype of mixed neuronal-glial tumor. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › nervous system neoplasm › neuroepithelial neoplasm › mixed neuronal-glial tumor › desmoplastic infantile astrocytoma

Related subtypes (11): ganglioneuroma, dysembryoplastic neuroepithelial tumor, extraventricular neurocytoma, gangliocytoma, desmoplastic infantile astrocytoma/ganglioglioma, ganglioglioma, papillary glioneuronal tumor, rosette-forming glioneuronal tumor of fourth ventricule, Lhermitte-Duclos disease, central neurocytoma, desmoplastic infantile ganglioglioma

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.