diffuse large B-cell lymphoma with chronic inflammation

Summary

diffuse large B-cell lymphoma with chronic inflammation (MONDO:0017601) is a cancer. A subtype of Epstein-Barr virus-associated lymphoproliferative disorder — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	diffuse large B-cell lymphoma with chronic inflammation
Mondo ID	MONDO:0017601
Orphanet	300888
NCIT	C80289
UMLS	C4511460
MedGen	1374328
GARD	0021250
Is cancer (heuristic)	yes

Also known as: DLBCL with chronic inflammation

Data availability: 9 cell lines.

Disease family

Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › virus associated tumor › Epstein-Barr virus-related tumor › Epstein-Barr virus-associated lymphoproliferative disorder › diffuse large B-cell lymphoma with chronic inflammation

Related subtypes (10): primary central nervous system lymphoma, Hodgkins lymphoma, Burkitt lymphoma, Epstein-Barr virus-positive diffuse large B-cell lymphoma of the elderly, plasmablastic lymphoma, systemic Epstein-Barr virus-positive T-cell lymphoproliferative disease of childhood, hydroa vacciniforme-like lymphoma, primary effusion lymphoma, lymphomatoid granulomatosis, extranodal nasal NK/T cell lymphoma

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.