Dissociative disorder
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Summary
Dissociative disorder (MONDO:0001160) is a disease and 15 clinical trials. Top therapeutic interventions include ketamine hydrochloride and sertraline. A subtype of psychiatric disorder — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Clinical trials: 15
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | dissociative disorder |
| Mondo ID | MONDO:0001160 |
| MeSH | D004213 |
| DOID | DOID:10935 |
| NCIT | C92197 |
| UMLS | C0012746 |
| MedGen | 3871 |
| Is cancer (heuristic) | no |
Disease family
This is a subtype of psychiatric disorder. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by developmental or physiological process › psychiatric disorder › dissociative disorder
Related subtypes (13): sexual disorder, impulse control disorder, personality disorder, cognitive disorder, factitious disorder, substance-related disorder, somatoform disorder, mental disorder, eating disorder, enuresis, Alice in Wonderland syndrome, catatonia, body integrity dysphoria
Subtypes (3): multiple personality disorder, dissociative amnesia, depersonalization disorder
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 15.
Phase distribution (across all retrieved trials)
| Phase | Trials |
|---|---|
| Not specified | 13 |
| PHASE4 | 1 |
| EARLY_PHASE1 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT00835627 | PHASE4 | COMPLETED | Treatment Trial for Psychogenic Nonepileptic Seizures |
| NCT06235177 | EARLY_PHASE1 | NOT_YET_RECRUITING | Psychoneuromentalism Disorder: A Medical Condition That Affects People With Psychological Impairments From Health Issues |
| NCT05565352 | Not specified | ENROLLING_BY_INVITATION | Ketamine Safety and Tolerability in Psychiatric Inpatient Care (KetGD) |
| NCT06330467 | Not specified | RECRUITING | Prevalence of Dissociative Identity Disorder in At-risk Outpatient Groups Reporting Childhood Trauma. |
| NCT06917209 | Not specified | RECRUITING | Evaluation of the Efficacy of Dissociation-Focused Cognitive Behavior Therapy |
| NCT00630981 | Not specified | UNKNOWN | Psychotherapy and Pharmacotherapy in Dissociative Disorders |
| NCT01388140 | Not specified | UNKNOWN | Psychopathology of Dissociative Disorders |
| NCT01512641 | Not specified | COMPLETED | Prevalence of Dissociative Disorders in Children |
| NCT02007928 | Not specified | COMPLETED | Assessment of Adverse Events in a Naive Pediatric Population Treated With an Antipsychotic |
| NCT02325544 | Not specified | COMPLETED | Comparing Different Treatments in Reducing Dissociative Seizure Occurrence |
| NCT02450617 | Not specified | COMPLETED | Stabilizing Group Treatment of Complex Trauma: A Randomized Controlled Trial |
| NCT02565524 | Not specified | COMPLETED | the Phenotypic and Genetic Profile of Patients With Early Onset Schizophrenia Associated With Autism Spectrum Disorder. |
| NCT04813224 | Not specified | UNKNOWN | Intervention Through EMDR and CBT With Women Victim of Childhood Sexual Abuse. A Randomized Controlled Trial. |
| NCT05081778 | Not specified | COMPLETED | Dissociative Disorders in Obesity (Dissobe) |
| NCT06054009 | Not specified | COMPLETED | Dissociation CBT Studies |
Drugs tested across these trials (top 30)
| Molecule | Max phase | Trials referencing |
|---|---|---|
| KETAMINE HYDROCHLORIDE | 4 | 1 |
| SERTRALINE | 4 | 1 |
| CHEMBL1788361 | 0 | 1 |
Related Atlas pages
- Drugs: Ketamine, Sertraline