Duodenal obstruction

Summary

Duodenal obstruction (MONDO:0002688) is a disease and 4 clinical trials. A subtype of duodenal disorder — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 4

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	duodenal obstruction
Mondo ID	MONDO:0002688
MeSH	D004380
DOID	DOID:3558
ICD-11	1450844990
SNOMED CT	95532008
UMLS	C0013292
MedGen	4417
Is cancer (heuristic)	no

Disease family

This is a subtype of duodenal disorder. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › digestive system disorder › intestinal disorder › small intestine disorder › duodenal disorder › duodenal obstruction

Related subtypes (5): duodenitis, duodenal ulcer, biliary dyskinesia, duodenogastric reflux, tumor of duodenum

Subtypes (3): chronic duodenal ileus, superior mesenteric artery syndrome, pancreatic lipomatosis duodenal stenosis

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 4.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	4

Top trials by phase / activity

NCT	Phase	Status	Title
NCT06642805	Not specified	NOT_YET_RECRUITING	Bilio-pancreatic Complications of Congenital Duodenal Obstructions
NCT00991614	Not specified	COMPLETED	EVOLUTION® Duodenal Stent for Duodenal or Gastric Outlet Obstruction Caused by Malignant Neoplasms
NCT03125148	Not specified	COMPLETED	Comparison of Duodenal Stenting vs Transpyloric and Duodenal Stenting for Malignant Obstruction
NCT06970093	Not specified	COMPLETED	Comparison of One Anastomisis Gastric Bypass and Duodeno-Jejunostomy for Treating SMA Syndrome