Endemic goiter

Summary

Endemic goiter (MONDO:0006742) is a disease. A subtype of goiter — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	endemic goiter
Mondo ID	MONDO:0006742
EFO	EFO:1000916
MeSH	D006043
DOID	DOID:13198
NCIT	C35023
SNOMED CT	56805008
UMLS	C0018022
MedGen	5357
MedDRA	10068848
Is cancer (heuristic)	no

Also known as: iodine-deficiency-related endemic goiter · simple goiter

Disease family

This is a subtype of goiter. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › endocrine system disorder › thyroid gland disorder › goiter › endemic goiter

Related subtypes (6): toxic diffuse goiter, dyshormonogenic goiter, nontoxic goiter, lingual goiter, nodular goiter, substernal goiter

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.