Endometrial disorder

Summary

Endometrial disorder (MONDO:0000931) is a disease (an umbrella term covering 7 Mondo subtypes) and 7 clinical trials. Top therapeutic interventions include misoprostol acid. A subtype of uterine disorder — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Umbrella term: 7 Mondo subtypes
• Clinical trials: 7

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	endometrial disorder
Mondo ID	MONDO:0000931
DOID	DOID:1005
NCIT	C3504
SNOMED CT	418632009
UMLS	C0151622
MedGen	57473
Anatomy (UBERON)	UBERON:0001295
Is cancer (heuristic)	no

Also known as: disease of endometrium · disease or disorder of endometrium · disorder of endometrium · endometrial disorder · endometrium disease · endometrium disease or disorder

Disease family

This is a subtype of uterine disorder. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › reproductive system disorder › female reproductive system disorder › uterine disorder › endometrial disorder

Related subtypes (20): pyometritis, female infertility of uterine origin, uterine inflammatory disease, chronic subinvolution of uterus, adhesions of uterus, cervix disorder, uterine polyp, pelvic congestion syndrome, uterine inversion, placenta disorder, hemometra, parametritis, cordiform uterus, septate uterus, bicornuate uterus, uterine hypoplasia, agenesis and aplasia of uterine body, tumor of uterus, florid cystic endosalpingiosis of the uterus, pregnancy, cornual

Subtypes (7): endometritis, tamoxifen-related endometrial lesion, endometriosis, atypical endometrial hyperplasia, endometrial polyp, adenomyosis, endometrium neoplasm

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 7.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	5
PHASE3	1
PHASE2	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT01805115	PHASE3	COMPLETED	Misoprostol Administration Before Operative Hysteroscopy
NCT03067623	PHASE2	UNKNOWN	Autologous Platelet-Rich Plasma (PRP) and Endometrial Thickness
NCT06763393	Not specified	ACTIVE_NOT_RECRUITING	Correlation Between Adnexal Masses and Endometrial Thickness Measured With Ultrasound in Adults Women
NCT03351673	Not specified	UNKNOWN	Endometrial Volume as a Predictor of Endometrial Pathology in Perimenopausal Uterine Bleeding Endometrial Volume as a Predictor of Endometrial Pathology in Perimenopausal Uterine Bleeding
NCT04363879	Not specified	COMPLETED	Comparing Two Types of Endometrial Activation Prior to Embryo Transfer
NCT04454749	Not specified	TERMINATED	Endometrial Compaction and Its Influence on Pregnancy Rate in Frozen Embryo Cycle Regimes
NCT05157373	Not specified	UNKNOWN	The Effect of Androgen Receptor Polymorphism on Endometrial Cancer

Drugs tested across these trials (top 30)

Molecule	Max phase	Trials referencing
MISOPROSTOL ACID	-1	1